M1629

Medroxyprogesterone 17-acetate

synthetic (organic), ≥97% (HPLC), synthetic progestogen, powder

• Sinonimo/i: 17α-Acetoxy-6α-methylprogesterone, 17α-Hydroxy-6α-methyl-4-pregnene-3,20-dione 17-acetate, 6α-Methyl-17α-acetoxyprogesterone, 6α-Methyl-17α-hydroxyprogesterone acetate
• Formula empirica (notazione di Hill): C₂₄H₃₄O₄
• Numero CAS: 71-58-9
• Peso molecolare: 386.52
• NACRES: NA.77
• PubChem Substance ID: 24896674
• UNSPSC Code: 12352200
• EC Number: 200-757-9
• MDL number: MFCD00010483
• Beilstein/REAXYS Number: 2066112
• Assay: ≥97% (HPLC)
• Form: powder

Proprietà

• Nome del prodotto: Medroxyprogesterone 17-acetate, ≥97% (HPLC)
• biological source: synthetic (organic)
• Quality Segment: 100
• sterility: non-sterile
• assay: ≥97% (HPLC)
• form: powder
• mp: 206-207 °C (lit.)
• solubility: chloroform: 350 mg/mL, clear, colorless
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [H][C@@]12C[C@H](C)C3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(OC(C)=O)C(C)=O
• InChI: 1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3/t14-,18+,19-,20-,22+,23-,24-/m0/s1
• InChI key: PSGAAPLEWMOORI-PEINSRQWSA-N
• Gene Information: human ... AR(367), ESR1(2099), ESRRA(2101), NR3C1(2908), NR3C2(4306), PGR(5241) ; rat ... Ar(24208)

Descrizione

Biochem/physiol Actions

Medroxyprogesterone 17-acetate (MPA) is a synthetic progestin used as a contraceptive, in hormone replacement therapy and for the treatment of endometriosis. It is a more potent progestin that the nonacetylated form.

Features and Benefits

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informazioni sulla sicurezza

• pictograms: GHS08
• signalword: Warning
• hcodes: H351,H413
• pcodes: P202 - P273 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Aquatic Chronic 4 - Carc. 2
• Classe di stoccaggio: 11 - Combustible Solids
• wgk: WGK 3
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges