This human serum used to prepare this product is from a pool of approximately 50 donors.
C9473
Complement Serum Standard human
aqueous solution
Sinonimo/i:
Human Complement Serum
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1 ML
470,00 €
470,00 €
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Cambia visualizzazione
1 ML
470,00 €
About This Item
Codice UNSPSC:
12352202
NACRES:
NA.61
470,00 €
Per informazioni sulla disponibilità, contatta il Servizio Clienti.
Prodotti consigliati
Origine biologica
human
Livello qualitativo
Stato
aqueous solution
applicazioni
cell analysis
Condizioni di spedizione
dry ice
Temperatura di conservazione
−70°C
Descrizione generale
The complement serum standard human is suitable for the determination of CH50 and AP50 complement activities. This allows for a test of the complement activity on the capacity of the serum to lyse red blood cells in vitro and can be used in procedures for genotyping DNA samples of the complement system.
Applicazioni
Complement Serum Standard human has been used as a positive control to study the role of the complement system in immunological demyelination of the spinal cord from mammals.[1]
Azioni biochim/fisiol
The complement system is an important constituent of innate immunity.[2] It participates in the first line of defense against microbial infections, altered host cells, and removal of immune complexes and injured cells. The complement system comprises more than thirty components such as the plasma proteins produced by the liver, membrane proteins expressed on the cell surface, cytokines, and hormones.[2][3] The complement proteins come together to opsonize the pathogens and initiate a cascade of inflammatory responses serving the immune cells to fight the infection and maintain homeostasis.[2]
Stato fisico
Supplied as a 0.22 μm filtered solution containing ~ 18 mM citrate, ~22 mM dextrose, ~3 mM phosphate and ~13 mM calcium
Esclusione di responsabilità
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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I clienti hanno visto anche
Marina Noris et al.
Seminars in nephrology, 33(6), 479-492 (2013-10-29)
Complement is an important component of the innate immune system that is crucial for defense from microbial infections and for clearance of immune complexes and injured cells. In normal conditions complement is tightly controlled by a number of fluid-phase and
J K Dyer et al.
Spinal cord, 43(7), 417-425 (2005-05-18)
Specificity of serum complement component to elicit immunological demyelination. To assess the role of complement components and pathways in experimental immunological demyelination of the adult rat spinal cord. ICORD, University of British Columbia, Vancouver, Canada. We used 32 adult male
Nicolas S Merle et al.
Frontiers in immunology, 6, 262-262 (2015-06-18)
Complement is a complex innate immune surveillance system, playing a key role in defense against pathogens and in host homeostasis. The complement system is initiated by conformational changes in recognition molecular complexes upon sensing danger signals. The subsequent cascade of
Risk Alleles in CFH and ARMS2 Are Independently Associated with Systemic Complement Activation in Age-related Macular Degeneration.
Smailhodzic D., et al.
Ophthalmology (2011)
Jordan E Inglis et al.
Advances in physiology education, 32(4), 317-321 (2008-12-03)
The immune system is a vital physiological component that affords animals protection from disease and is composed of innate and adaptive mechanisms that rely on cellular and dissolved components. The serum complement system is a series of dissolved proteins that
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