If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf
PHR1810
Tadalafil
Pharmaceutical Secondary Standard; Certified Reference Material
Sinonimo/i:
Tadalafil
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About This Item
Prodotti consigliati
Grado
certified reference material
pharmaceutical secondary standard
Livello qualitativo
agenzia
traceable to Ph. Eur. Y0001417
traceable to USP 1642879
Famiglia di API
tadalafil
Stato
powder
CdA
current certificate can be downloaded
Confezionamento
pkg of 500 mg
tecniche
HPLC: suitable
gas chromatography (GC): suitable
applicazioni
pharmaceutical (small molecule)
Temperatura di conservazione
2-30°C
Stringa SMILE
N21[C@H](Cc3c4c([nH]c3[C@H]2c5cc6c(cc5)OCO6)cccc4)C(=O)N(CC1=O)C
InChI
1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1
WOXKDUGGOYFFRN-IIBYNOLFSA-N
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Descrizione generale
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Tadalafil is a phosphodiesterase type 5 inhibitor that prevents the hydrolysis of cyclic adenosine monophosphate and cyclic guanosine monophosphate.[1]
Applicazioni
- Square-wave voltammetric (SWV) determination of tadalafil in pharmaceutical samples using a boron-doped diamond electrode (BDDE)[2]
- Development of multi-walled and vertically oriented carbon nanotubes (voMWCNT) based electrochemical sensor for the detection of tadalafil in pharmaceutical samples[1]
- Simultaneous determination of sildenafil, tadalafil, and vardenafil in pharmaceutical preparations by a high-temperature gas chromatography/mass spectrometry (HTGC/MS) method[3]
- Development and validation of spectrophotometric methods for the combined analysis of dapoxetine hydrochloride and tadalafil in bulk and pharmaceutical dosage forms
- Spectrophotometric quantification of tamsulosin hydrochloride and tadalafil in their combined pharmaceutical preparation, following International Conference on Harmonization (ICH) guidelines[4]
Risultati analitici
Nota a piè di pagina
Prodotti correlati
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Organi bersaglio
Respiratory system
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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Certificati d'analisi (COA)
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How can I determine the shelf life / expiration / retest date of this product?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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