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I2399

Sigma-Aldrich

Imidazolo

ACS reagent, ≥99% (titration)

Sinonimo/i:

1,3-diaza-2,4-ciclopentadiene, Gliossalina

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About This Item

Formula empirica (notazione di Hill):
C3H4N2
Numero CAS:
288-32-4
Peso molecolare:
68.08
Beilstein:
103853
Numero CE:
206-019-2
Numero MDL:
MFCD00005183
Codice UNSPSC:
12352005
eCl@ss:
39161001
ID PubChem:
24895975
NACRES:
NA.21

Grado

ACS reagent

Livello qualitativo

200

Tensione di vapore

<1 mmHg ( 20 °C)

Saggio

≥99% (titration)

Impurezze

≤0.2% water

Residuo alla calcinazione

≤0.1%

pH

9.5-11.0 (25 °C, 5% in H2O)

pKa (25 °C)

6.95

P. eboll.

256 °C (lit.)

Punto di fusione

88-91 °C (lit.)

Cationi in tracce

Fe: ≤0.001%

Stringa SMILE

c1c[nH]cn1

InChI

1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)
RAXXELZNTBOGNW-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

Imidazole is a five-membered heterocycle that is found in many naturally occurring compounds. It exhibits both acidic and basic properties. It is reported to be an inhibitor of thromboxane formation. Its vertical spectrum and the radiationless decay have been recorded and analyzed.

Applicazioni

Ottimo per tamponi nell′intervallo di pH 6,2-7,8

Altre note

Go to Redi-Dri™ Product Listing 792527

Note legali

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Avvertenze

Danger

Indicazioni di pericolo

H302,H314,H360D

Classi di pericolo

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

293.0 °F - closed cup

Punto d’infiammabilità (°C)

145 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
0000306815
0000306817
0000306815
0000305341
0000288351

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Imidazolo

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Sigma-Aldrich

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Sigma-Aldrich

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S Moncada et al.
Prostaglandins, 13(4), 611-618 (1977-04-01)
Imidazole inhibits the enzymic conversion of the endoperoxides (PGG2 and PGH2) to thromboxane A2 by platelet microsomes (IC50: 22 MICRONG/ML; DETERMINED BY BIOASSAY). The inhibitor is selective, for prostaglandin cyclo-oxygenase is only affected at high doses. Radiochemical data confirms that
UV excitation and radiationless deactivation of imidazole.
Barbatti M, et al.
J. Chem. Phys. , 130(3), 034305-034305 (2009)
Zhong Jin
Natural product reports, 28(6), 1143-1191 (2011-04-08)
A great number of structurally diverse natural products containing five-membered heterocyclic subunits, such as imidazole, oxazole, thiazole, and their saturated congeners, are abundant in nature. These naturally occurring metabolites often exhibit extensive and pharmacologically important biological activities. The latest progress
Peter Canning et al.
Journal of molecular biology, 426(13), 2457-2470 (2014-04-29)
The discoidin domain receptors (DDRs), DDR1 and DDR2, form a unique subfamily of receptor tyrosine kinases that are activated by the binding of triple-helical collagen. Excessive signaling by DDR1 and DDR2 has been linked to the progression of various human
Pam M Van Ry et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 23(8), 1285-1297 (2015-06-09)
Duchenne muscular dystrophy (DMD) is a fatal neuromuscular disease caused by mutations in the dystrophin gene, leading to the loss of a critical component of the sarcolemmal dystrophin glycoprotein complex. Galectin-1 is a small 14 kDa protein normally found in skeletal
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