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A7409

Sigma-Aldrich

Albumina sierica bovina

35% in 0.85% sodium chloride, aseptically filled

Sinonimo/i:

Albumina, Soluzione di BSA

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10 ML
177,00 €
50 ML
323,00 €
1 L
2.030,00 €

177,00 €


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Cambia visualizzazione
10 ML
177,00 €
50 ML
323,00 €
1 L
2.030,00 €

About This Item

Numero CAS:
Numero MDL:
Codice UNSPSC:
12352202
NACRES:
NA.27

177,00 €


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Origine biologica

bovine

Livello qualitativo

Descrizione

contains no preservative

Sterilità

aseptically filled

Stato

solution

Purificato mediante

heat shock fractionation

Origine

USA origin

Concentrazione

33.0-37.4% protein (biuret)
35% in 0.85% sodium chloride

tecniche

microbiological culture: suitable

N° accesso UniProt

Temperatura di conservazione

2-8°C

Informazioni sul gene

bovine ... ALB(280717)

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Descrizione generale

Albumin belongs to the four-member albumin superfamily.[1] It is a major protein in the circulating blood.[2] Albumin has a helical structure with three domains that form a heart-like shape.[1]

Applicazioni

Bovine Serum Albumin solution has been used:
  • to block protein-coated well plates in enzyme-linked immunosorbent assay (ELISA) for immunoreactivity and cross-reactivity studies in the production of monoclonal antibodies (mAbs)[3]
  • to prepare primary antibody solution for peroxidases staining[4]
  • as a supplement for in vitro cultivation of Borrelia strains[4]

Azioni biochim/fisiol

Bovine serum albumin (BSA) serves as a protein supplement for cell culture media.[5] BSA acts as a transport carrier for drugs, and it is commonly used to study the protein-drug interactions. Furthermore, it is known for its ability to interact with several aromatic and hydrophobic molecules of the bloodstream.[6]

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves


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Fatai S Oladunni et al.
Journal of virological methods, 290, 114084-114084 (2021-01-30)
The use of monoclonal neutralizing antibodies (mNAbs) is being actively pursued as a viable intervention for the treatment of Severe Acute Respiratory Syndrome CoV-2 (SARS-CoV-2) infection and associated coronavirus disease 2019 (COVID-19). While highly potent mNAbs have great therapeutic potential
Bovine serum albumin
Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, 1045 null
Ines Martin-Martin et al.
Cold Spring Harbor protocols, 2022(10), Pdb-Pdb (2022-08-13)
Immunohistochemistry is a valuable technique that provides information on protein localization and interactions in tissues. Mosquito salivary gland immunohistochemistry requires the meticulous dissection of a delicate tissue. The integrity of the salivary glands must be closely monitored throughout the entire
Paul A Wilson et al.
PloS one, 16(10), e0258316-e0258316 (2021-10-22)
RORγt is an isoform of RORC, preferentially expressed in Th17 cells, that functions as a critical regulator of type 3 immunity. As murine Th17-driven inflammatory disease models were greatly diminished in RORC knock-out mice, this receptor was prioritised as an
Sabrina Hepner et al.
Ticks and tick-borne diseases, 10(5), 1157-1161 (2019-06-27)
Borrelia turcica is a reptile-associated Borrelia species that is vectored by the hard tick Hyalomma aegyptium. Tortoises of the genus Testudo represent the principal host of adult H. aegyptium, while immature stages are less host-specific and can be found on

Domande

  1. Is the BSA cat. A7409 suitable for MACS buffer used for T cell separation? Separated cells would be cultured for around 2 weeks

    1 risposta
    1. This product has not been tested for suitability in this application. While it is aseptically prepared, this product is not tested for sterility.

      See product A7979 for the sterile, cell culture tested BSA solution that may be more suitable: https://www.sigmaaldrich.com/product/sigma/a7979

      In addition, see product A9418 to review another cell culture tested product that is cited for use in MACS buffer: https://www.sigmaaldrich.com/product/sigma/a9418

      A link to this publication is below:
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059065/

      Utile?

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Nessuna valutazione

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