12667-M
Human Serum Albumin
Albumin, Human Serum, 30% Aqueous Solution
30% Aqueous Solution
Sinonimo/i:
Albumin, Human Serum, 30% Aqueous Solution
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12667-50ML
481,00 €
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12667-50ML
481,00 €
About This Item
Prodotti consigliati
Nome del prodotto
Albumin, Human Serum, 30% Aqueous Solution,
Origine biologica
human
Descrizione
Merck USA index - 14, 8468
Saggio
≥95% (agarose gel electrophoresis)
Stato
liquid
Produttore/marchio commerciale
Calbiochem®
Condizioni di stoccaggio
OK to freeze
tecniche
cell culture | mammalian: suitable
Temperatura di conservazione
2-8°C
Stringa SMILE
FC(F)(F)C(F)(F)C(F)(F)F
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
QYSGYZVSCZSLHT-UHFFFAOYSA-N
Descrizione generale
Human serum albumin (HSA) is a soluble, globular, and unglycosylated monomeric protein,[1] which is abundantly found in the plasma.[2] It contains three homologous domains, numbered I, II, and III.[3] Each domain is divided into subdomains A and B comprising common structural motifs. The HSA gene is localized to the human chromosome 4q13.3.[3]
Azioni biochim/fisiol
Human serum albumin (HSA) acts as the most important carrier protein for fatty acids, thyroid hormones, and steroids.[1] It serves as a supplement in cell culture medium for the generation of vaccines and pharmaceuticals.[1] HSA acts as a valuable biomarker for diseases, such as severe acute graft-versus-host disease, cancer, and rheumatoid arthritis.[2] It is clinically used to treat serious burn injuries, hemorrhagic shock, hypoproteinemia, and fetal erythroblastosis.[1] HSA is used in biological applications including nano delivery of drugs, carrier of oxygen, and fusion of peptides.[1]
Attenzione
Toxicity: Standard Handling (A)
Stato fisico
30% solution in 20 mM Tris-HCl, 0.1% NaN₃, pH 6-8.
Nota sulla preparazione
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Note legali
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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I clienti hanno visto anche
Gabriella Fanali et al.
Molecular aspects of medicine, 33(3), 209-290 (2012-01-11)
Human serum albumin (HSA), the most abundant protein in plasma, is a monomeric multi-domain macromolecule, representing the main determinant of plasma oncotic pressure and the main modulator of fluid distribution between body compartments. HSA displays an extraordinary ligand binding capacity
Angelica M Merlot et al.
Frontiers in physiology, 5, 299-299 (2014-08-28)
Serum albumin is a multi-functional protein that is able to bind and transport numerous endogenous and exogenous compounds. The development of albumin drug carriers is gaining increasing importance in the targeted delivery of cancer therapy, particularly as a result of
Yang He et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(47), 19078-19083 (2011-11-02)
Human serum albumin (HSA) is widely used in clinical and cell culture applications. Conventional production of HSA from human blood is limited by the availability of blood donation and the high risk of viral transmission from donors. Here, we report
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