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860501P

Avanti

C22 Ceramide (d18:1/22:0)

Avanti Research™ - A Croda Brand 860501P, powder

Sinonimo/i:

N-behenoyl-D-erythro-sphingosine

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5 MG
215,00 €
10 MG
384,00 €

215,00 €

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Cambia visualizzazione
5 MG
215,00 €
10 MG
384,00 €

About This Item

Formula empirica (notazione di Hill):
C40H79NO3
Numero CAS:
27888-44-4
Peso molecolare:
622.06
Numero MDL:
MFCD09840213
Codice UNSPSC:
12352211
NACRES:
NA.25

215,00 €

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Richiedi un ordine bulk

Stato

powder

Confezionamento

pkg of 1 × 10 mg (860501P-10mg)
pkg of 1 × 5 mg (860501P-5mg)

Produttore/marchio commerciale

Avanti Research™ - A Croda Brand 860501P

Tipo di lipide

sphingolipids

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C40H79NO3/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-24-26-28-30-32-34-36-40(44)41-38(37-42)39(43)35-33-31-29-27-25-23-16-14-12-10-8-6-4-2/h33,35,38-39,42-43H,3-32,34,36-37H2,1-2H3,(H,41,44)/b35-33+/t38-,39+/m0/s1
KEPQASGDXIEOIL-GLQCRSEXSA-N

Descrizione generale

C22 Ceramide (d18:1/22:0) or N-behenoyl-D-erythro-sphingosine is a synthetic ceramide containing sphingosine with behenic acid.

Applicazioni

C22 Ceramide (d18:1/22:0) has been used:
  • as a standard to measure ceramide concentrations in muscle tissue samples using high-performance liquid chromatography/tandem mass spectrometry (LC/MS2)[1]
  • as a standard for the quantitation of sphingolipid metabolites[2]
  • to study its effects on mitochondrial-to-cytosolic stress response (MCSR) induction[3]

Azioni biochim/fisiol

Ceramides plays an important role in regulating cell differentiation, proliferation and apoptosis. It also regulates stress responses and inflammation.[4]

Confezionamento

5 mL Amber Glass Screw Cap Vial (860501P-10mg)
5 mL Amber Glass Screw Cap Vial (860501P-5mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Comunemente ordinati con questo prodotto

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

11 - Combustible Solids

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Certificati d'analisi (COA)

Lot/Batch Number

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Sigma-Aldrich

43799

N-Palmitoyl-D-sphingosine

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845875P

18:1 Lyso PC

Hyun-Eui Kim et al.
Cell, 166(6), 1539-1552 (2016-09-10)
Defects in mitochondrial metabolism have been increasingly linked with age-onset protein-misfolding diseases such as Alzheimer's, Parkinson's, and Huntington's. In response to protein-folding stress, compartment-specific unfolded protein responses (UPRs) within the ER, mitochondria, and cytosol work in parallel to ensure cellular
Xingzhong Zhang et al.
Cell metabolism, 30(5), 937-951 (2019-11-02)
Obesity-induced adipose dysfunction is a major contributor to atherosclerosis. Cold exposure has been reported to affect atherosclerosis through regulation of adipose function, but the mechanism has not been well clarified. Here, adipocyte hypoxia-inducible factor 2α (HIF-2α) was upregulated after mild cold
Mutay Aslan et al.
Nutrition and cancer, 1-13 (2020-04-15)
We aimed to investigate the impact of thymoquinone (TQ), on sphingolipid metabolites, ER stress and apoptotic pathways in MCF-7 and HepG2 cancer cells. Antiproliferative effect was exerted in cancer cells via TQ incubation at different doses and durations. Cell viability
Ebru Afşar et al.
Redox biology, 30, 101430-101430 (2020-01-25)
We aimed to determine sphingolipid levels and examine apoptotic pathways in human retinal pigment epithelial cells (ARPE-19) undergoing endoplasmic reticulum (ER) stress. Cells were treated with tunicamycin (TM) to induce ER stress and tauroursodeoxycholic acid (TUDCA), an ER stress inhibitor
Dimple Kauhanen et al.
Analytical and bioanalytical chemistry, 408(13), 3475-3483 (2016-02-29)
Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the prediction of fatal outcome of coronary artery disease (CAD). We describe a validated liquid chromatography-tandem mass spectrometry
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