791637C

15:0-18:1-d7-PC

Avanti Research^™ - A Croda Brand

• Sinonimo/i: 1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphocholine
• Formula empirica (notazione di Hill): C₄₁H₇₃ D₇ NO₈ P
• Numero CAS: 2097561-16-3
• Peso molecolare: 753.09
• Numero MDL: MFCD22570234
• Codice UNSPSC: 41141825
• NACRES: NA.25

Proprietà

• Saggio: >99% (TLC)
• Stato: liquid
• Confezionamento: pkg of 1 × 1 mL (791637C-1mg)
• Produttore/marchio commerciale: Avanti Research^™ - A Croda Brand
• Concentrazione: 1 mg/mL (791637C-1mg)
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

15:0-18:1-d7-PC (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphocholine) is a deuterated phospholipid. The lipid comprises phosphatidylcholine attached to pentadecanoic acid and oleic acid. Oleic acid harbors the deuterium ions. Phospholipids, in general are amphiphilic and have phosphocholine moiety attached to sn-3 position of glycerol.[1] Phosphatidylcholine is a glycerophospholipid and is a cell membrane component.[2]

This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH^™ LIPIDOMIX^™ Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

Applicazioni

15:0-18:1-d7-PC (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphocholine) has been used:

• as a component of extraction solvent for lipid isolation from biological samples [3]
• as an internal standard for spiking serum samples for liquid chromatography with tandem mass spectrometry (LC-MS/MS)[4]
• as an internal standard in analysis of lipids from cystic fibrosis derived cell lines[5]

Azioni biochim/fisiol

Phosphatidylcholine (PC) levels are crucial for mediating various cellular processes including membrane movement and cell differentiation.[2] A disturbance in PC levels is implicated in various metabolic disorders.[6]

Confezionamento

2 mL Amber Glass Sealed Ampule (791637C-1mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC

SPLASH is a trademark of Avanti Polar Lipids, LLC

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Consigli di prudenza: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Classi di pericolo: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Organi bersaglio: Central nervous system, Liver,Kidney
• Codice della classe di stoccaggio: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): does not flash
• Punto d’infiammabilità (°C): does not flash