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Merck

HTR3A

5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

Sinonimi:
5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3
Specie:
Human HTR3A (3359), Mouse Htr3a (15561), Rat Htr3a (79246), Domestic Rabbit HTR3A (100009570), chicken HTR3A (428247), domestic guinea pig Htr3a (100135547), Horse HTR3A (100009690), naked mole-rat Htr3a (101714088), sheep HTR3A (101110536), dog HTR3A (489399) ...Più
ID UniProtKB:
P46098, B4DSY6, G5E986, O60854, Q7KZM7, Q99918, Q9BSZ9
ID gene:
  • Human(3359) Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15561) 5-hydroxytryptamine (serotonin) receptor 3A
  • Rat(79246) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • Domestic Rabbit(100009570) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • chicken(428247) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • domestic guinea pig(100135547) 5-hydroxytryptamine (serotonin) receptor 3A
  • Horse(100009690) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • naked mole-rat(101714088) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • sheep(101110536) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • dog(489399) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • cow(617674) 5-hydroxytryptamine (serotonin) receptor 3A
  • domestic cat(101098004) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
32473
Metoclopramide, VETRANAL®, analytical standard,
Specie
human
M1824990
Metoclopramide, European Pharmacopoeia (EP) Reference Standard,
Specie
human
BP357
Metoclopramide hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Specie
human
S1688
SR 57227A, solid,
Specie
human
M0763
Metoclopramide hydrochloride, solid,
Specie
human

Small Molecule - Allosteric Modulator

N° Catalogo
Descrizione
Specie
D9190
DCEBIO, ≥98% (HPLC), solid,
Specie
human

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
H9523
Serotonina, powder,
Specie
human
H7752
Serotonin creatinine sulfate monohydrate, powder,
Specie
human
O3639
Ondansetron hydrochloride dihydrate, ≥98% (HPLC), powder,
Specie
human
73659
1-(4-Chlorophenyl)piperazine, ≥98.0% (GC),
Specie
rat
1478582
Ondansetron hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
HPA069442
Anti-HTR3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry
ABN1475
Anti-Serotonin receptor 3A/HTR3A, from rabbit, purified by affinity chromatography,
Reattività con
human
Applicazione
immunohistochemistry
western blot

Small Molecule - Blocker

N° Catalogo
Descrizione
Specie
T3146
Trimipramine maleate salt, ≥98% (TLC), powder,
Specie
human
Z101
Zimelidine dihydrochloride, solid,
Specie
human

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Specie
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Specie
human
F132
Fluoxetine hydrochloride, solid,
Specie
human
S6319
Sertraline hydrochloride, ≥98% (HPLC),
Specie
human
R0875
Reserpine, ,
Specie
human

Small Molecule - Ligand

N° Catalogo
Descrizione
Specie
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Specie
human

Small Molecule - Metabolite

N° Catalogo
Descrizione
Specie
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Specie
human

Small Molecule - Precursor

N° Catalogo
Descrizione
Specie
H9772
5-Hydroxy-L-tryptophan, powder,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
EMU053551
MISSION® esiRNA, targeting mouse Htr3a,
Specie
mouse
EHU080571
MISSION® esiRNA, targeting human HTR3A,
Specie
human