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Merck

ADRA2A

adrenoceptor alpha 2A

Sinonimi:
ADRA2, ADRA2R, ADRAR, ALPHA2AAR, ZNF32
Specie:
ID UniProtKB:
ID gene:
  • Human(150) Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
  • Mouse(11551) adrenergic receptor, alpha 2a
  • Rat(25083) adrenoceptor alpha 2A
  • domestic guinea pig(100135475) adrenergic receptor, alpha 2a
  • chicken(428980) adrenergic, alpha-2A-, receptor
  • sheep(100170317) adrenoceptor alpha 2A
  • Domestic Rabbit(100009424) adrenoceptor alpha 2A
  • Zebrafish(266750) adrenergic, alpha-2A-, receptor
  • dog(486888) adrenoceptor alpha 2A
  • domestic cat(664736) adrenoceptor alpha 2A
  • sheep(101117291) adrenoceptor alpha 2A
  • naked mole-rat(101723298) adrenoceptor alpha 2A
  • cow(282135) adrenergic, alpha-2A-, receptor

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
Clonidine hydrochloride, solid,
Specie
human
Xylazine hydrochloride, ≥99.0% (HPLC),
Specie
human
Guanfacine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Guanfacine hydrochloride, ≥98% (HPLC),
Specie
human
Guanabenz acetate salt, powder,
Specie
human

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
1-Naphthylmethylamine, 97%,
Specie
rat
Yohimbine hydrochloride, ≥98% (HPLC), powder,
Specie
human
1,2,3,4-Tetrahydroisoquinoline, 95%,
Specie
rat, human
Idazoxan hydrochloride, ,
Specie
human
RX 821002 hydrochloride, solid, ≥98% (HPLC),
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Adrenergic Receptor α-2A antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-ADRA2A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
canine, human, mouse, rat
Applicazione
ELISA
immunocytochemistry

immunofluorescence
Anti-ADRA2A antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
immunofluorescence
Anti-α2A Adrenergic Receptor antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse, pig, rat
Applicazione
immunohistochemistry
western blot

Small Molecule - Blocker

N° Catalogo
Descrizione
Specie
Mianserin hydrochloride, ,
Specie
human
Agmatine sulfate salt, ≥97%, powder,
Specie
human

Small Molecule - Mixed Agonist/Antagonist

N° Catalogo
Descrizione
Specie
UK 14,304, ,
Specie
human
BP897, >98% (HPLC), solid,
Specie
human, rat
(−)-Norepinephrine, ≥98%, crystalline,
Specie
human, rat
Haloperidol, powder,
Specie
human, rat
Clozapine, ,
Specie
human, rat

Proteins

N° Catalogo
Descrizione
Specie
ChemiSCREEN Human α2A Adrenergic Receptor Membrane Preparation, Human alpha2A GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Specie
human