PHL89159

Apigenin

phyproof^® Reference Substance

• Szinonimák: 4′,5,7-Trihydroxyflavone, 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone
• Tapasztalati képlet (Hill-képlet): C₁₅H₁₀O₅
• CAS-szám: 520-36-5
• Molekulatömeg: 270.24
• Beilstein: 262620
• MDL-szám: MFCD00006831
• UNSPSC kód: 41116107
• NACRES: NA.24

Tulajdonságok

• grade: primary reference standard
• termékcsalád: phyproof^® Reference Substance
• Teszt: ≥95.0% (HPLC)
• Forma: powder
• gyártó/kereskedő neve: PhytoLab
• mp: >300 °C (lit.)
• SMILES string: Oc1ccc(cc1)C2=CC(=O)c3c(O)cc(O)cc3O2
• InChI: 1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H
• Nemzetközi kémiai azonosító kulcs: KZNIFHPLKGYRTM-UHFFFAOYSA-N

Leírás

Általános leírás

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biokémiai/fiziológiai hatások

A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G₂/M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appear to be related to induction of p53. Inhibits PMA-mediated tumor promotion by inhibiting protein kinase C and the resulting suppression of oncogene expression. It has also been reported to inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.

Egyéb megjegyzések

This compound is commonly found in plants of the genus: achillea mentha pimpinella primula salvia silybum thymus

Jogi információk

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Biztonsági adatok

• Tárolási osztály kódja: 13 - Non Combustible Solids
• WGK: WGK 3