T8390

Testosterone 3-(O-carboxymethyl)oxime

• Szinonimák: 17β-Hydroxy-4-androsten-3-one 3-(O-carboxymethyl)oxime, 4-Androsten-17β-ol-3-one 3-(O-carboxymethyl)oxime
• Tapasztalati képlet (Hill-képlet): C₂₁H₃₁NO₄
• CAS-szám: 10190-93-9
• Molekulatömeg: 361.48
• MDL-szám: MFCD00056503
• UNSPSC kód: 51111800
• PubChem Substance ID: 24900526
• NACRES: NA.77

Tulajdonságok

• sterilitás: non-sterile
• Minőségi szint: 200
• Teszt: ≥98.00% (TLC)
• Forma: powder
• drug control: Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
• oldhatóság: ethanol: soluble 49-51 mg/mL, clear, colorless to faintly yellow
• kiszállítva: ambient
• tárolási hőmérséklet: room temp
• SMILES string: [H][C@@]12CCC3=CC(\CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@@H](O)CC[C@@]24[H])=N\OCC(O)=O
• InChI: 1S/C21H31NO4/c1-20-9-7-14(22-26-12-19(24)25)11-13(20)3-4-15-16-5-6-18(23)21(16,2)10-8-17(15)20/h11,15-18,23H,3-10,12H2,1-2H3,(H,24,25)/b22-14+/t15-,16-,17-,18-,20-,21-/m0/s1
• Nemzetközi kémiai azonosító kulcs: VDYLVWGBLQNNAW-UVTKPVMCSA-N

Leírás

Alkalmazás

Testosterone 3-(O-carboxymethyl)oxime has been used for the hormonal analysis of sexual dimorphism in the electric fish, Apteronotus. This testosterone derivative has also been used for developing environmental biosensors for the detection of testosterone in water samples.

Testosterone 3-(O-carboxymethyl)oxime has been used to prepare horseradish peroxidase (HRP)-labeled testosterone to measure plasma testosterone concentration by enzyme immunoassay.

Biokémiai/fiziológiai hatások

Androgens direct the development of male reproductive system and secondary sexual characteristics. Testosterone is an androgen that is secreted by the testis. This hormone is converted to dihydrotestosterone (DHT) by 5α reductase in the target tissues. Both DHT and testosterone require androgen receptor, a ligand-dependent nuclear transcription factor to mediate their biological functions.

Androgens direct the development of the male phenotype during embryogenesis and at puberty. Testosterone is an androgen that is secreted by the testis. This hormone is converted to dihydrotestosterone in the target tissues where it may mediate several biological functions.

Elkészítési megjegyzés

Testosterone 3-(O-carboxymethyl)oxime is soluble in ethanol at 49-51 mg/ml and yields a clear, colorless to faint yellow solution.

Biztonsági adatok

• Piktogramok: GHS08,GHS07
• Figyelmeztetés: Warning
• Figyelmeztető mondatok: H302 + H312 + H332,H351
• Óvintézkedésre vonatkozó mondatok: P202 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
• Veszélyességi osztályok: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges