SAB5702029

Anti-COX IV Antibody, clone 3P8J2, Rabbit Monoclonal

• Szinonimák: COX IV-1, COX4, COX4-1, COXIV, COXIV-1
• UNSPSC kód: 12352203
• NACRES: NA.46
• klón: 3P8J2, monoclonal
• application: IHC; WB
• faj reaktivitás: rat, rat, human
• technika/technikák: immunohistochemistry: 1:50 - 1:200; western blot: 1:500 - 1:2000

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• material: colorless
• klón: 3P8J2, monoclonal
• Forma: liquid
• molekulatömeg: 17 kDa
• faj reaktivitás: rat, rat, human
• koncentráció: 0.25 mg/mL
• technika/technikák: immunohistochemistry: 1:50 - 1:200; western blot: 1:500 - 1:2000
• szín: colorless
• izotípus: IgG
• immunogén szekvencia: MLATRVFSLVGKRAISTSVCVRAHESVVKSEDFSLPAYMDRRDHPLPEVAHVKHLSASQKALKEKEKASWSSLSMDEKVELYRIKFKESFAEMNRGSNEW
• UniProt elérési szám: P13073
• kiszállítva: wet ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... COX4I1(1327)

Leírás

Általános leírás

Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

Immunogén

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human COX IV (P13073).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Alkalmazás

WB, IHC

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 1