SAB5700883

Anti-LRP1 antibody produced in rabbit

• UNSPSC kód: 12352203
• NACRES: NA.41
• klón: monoclonal
• application: WB
• faj reaktivitás: rat, human, mouse
• technika/technikák: western blot: 1:500-1:2000

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• antitest terméktípus: primary antibodies
• klón: monoclonal
• Forma: liquid
• faj reaktivitás: rat, human, mouse
• koncentráció: 0.23 mg/mL
• technika/technikák: western blot: 1:500-1:2000
• UniProt elérési szám: Q07954
• kiszállítva: wet ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... LRP1(4035)

Leírás

Általános leírás

This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015]

Immunogén

A synthesized peptide derived from human LRP1

Fizikai forma

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Biztonsági adatok

• Tárolási osztály kódja: 12 - Non Combustible Liquids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable