SAB5700826

Anti-RAD51 antibody produced in rabbit

• Szinonimák: BRCC5, FANCR, HRAD51, HsRad51, HsT16930, MRMV2, RAD51, RAD51A, RECA
• UNSPSC kód: 12352203
• NACRES: NA.41
• klón: polyclonal
• application: WB
• faj reaktivitás: rat, mouse, human
• technika/technikák: western blot: 1:500-1:1000

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• antitest forma: affinity isolated antibody
• antitest terméktípus: primary antibodies
• klón: polyclonal
• Forma: buffered aqueous solution
• molekulatömeg: 26; 31; 36
• faj reaktivitás: rat, mouse, human
• koncentráció: 5.22 mg/ml
• technika/technikák: western blot: 1:500-1:1000
• UniProt elérési szám: Q06609
• kiszállítva: wet ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... RAD51(5888)

Leírás

Általános leírás

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogén

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human RAD51 (NP_002866.2).

Fizikai forma

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Tárolás és stabilitás

Store at -20℃. Avoid freeze / thaw cycles.

Biztonsági adatok

• Tárolási osztály kódja: 12 - Non Combustible Liquids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable