392M-1

Langerin (12D6) Mouse Monoclonal Antibody

• UNSPSC kód: 12352203
• NACRES: NA.41

Tulajdonságok

• biológiai forrás: mouse
• Minőségi szint: 100; 500
• konjugátum: unconjugated
• antitest forma: culture supernatant
• antitest terméktípus: primary antibodies
• klón: 12D6, monoclonal
• leírás: For In Vitro Diagnostic Use in Select Regions (See Chart)
• form: buffered aqueous solution
• faj reaktivitás: human
• kiszerelés: vial of 0.1 mL concentrate (392M-14); vial of 0.5 mL concentrate (392M-15); bottle of 1.0 mL predilute (392M-17); vial of 1.0 mL concentrate (392M-16); bottle of 7.0 mL predilute (392M-18)
• gyártó/kereskedő neve: Cell Marque^™
• technika/technikák: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
• izotípus: IgG2bκ
• szabályozó: Langerhans cell histiocytosis
• kiszállítva: wet ice
• tárolási hőmérséklet: 2-8°C
• vizualizáció: cytoplasmic
• Géninformáció: human ... CD207(50489)

Leírás

Általános leírás

Langerin is a type II transmembrane C-type lectin associated with the formation of Birbeck granules in Langerhans cells. The demonstration of langerin immunoreactivity is considered an adjunct or alternative to CD1a antigen expression as evidence to aid in the diagnosis of Langerhans cell histiocytosis. Evaluation of langerin expression is valuable in circumstances where a diagnosis of Langerhans cell histiocytosis is suspected, but cannot be confirmed due to lack of CD1a immunoreactivity. A panel of antibodies against CD1a, langerin, CD21, CD23, CD35 and S100 is very useful in the distinction of Langerhans cell histiocytosis, histiocytic sarcoma, interdigitating dendritic cell sarcoma, follicular dendritic cell sarcoma, disseminated juvenile xanthogranuloma, and Rosai-Dorfman disease (sinus histiocytosis with massive lymphadenopathy).

Minőség

IVD

IVD

IVD

RUO

Kapcsolódás

Langerin Positive Control Slides, Product No. 392S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Fizikai forma

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Elkészítési megjegyzés

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Egyéb megjegyzések

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Jogi információk

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Tárolási osztály kódja: 12 - Non Combustible Liquids
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable