PHR1720

Clomipramine hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

• Szinonimák: Clomipramine hydrochloride, 3-Chloro-10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine hydrochloride, Anafranil hydrochloride
• Tapasztalati képlet (Hill-képlet): C₁₉H₂₃ClN₂ · HCl
• CAS-szám: 17321-77-6
• Molekulatömeg: 351.31
• EC-szám: 241-344-3
• MDL-szám: MFCD00069234
• UNSPSC kód: 41116107
• PubChem Substance ID: 329823573
• NACRES: NA.24

Tulajdonságok

• grade: certified reference material; pharmaceutical secondary standard
• Minőségi szint: 300
• Ügynökség: traceable to BP; traceable to Ph. Eur. C2360000; traceable to USP 1140427
• API-család: clomipramine
• Analitikai műbizonylat: current certificate can be downloaded
• kiszerelés: pkg of 1 g
• technika/technikák: HPLC: suitable; gas chromatography (GC): suitable
• alkalmazás(ok): pharmaceutical (small molecule)
• Formátum: neat
• tárolási hőmérséklet: 2-30°C
• SMILES string: Cl.CN(C)CCCN1c2ccccc2CCc3ccc(Cl)cc13
• InChI: 1S/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22;/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3;1H
• Nemzetközi kémiai azonosító kulcs: WIMWMKZEIBHDTH-UHFFFAOYSA-N
• Géninformáció: human ... SLC6A4(6532)

Leírás

Általános leírás

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Clomipramine hydrochloride is one of the dibenzazepine tricyclic antidepressants that inhibits noradrenalin and serotonin reuptake in central nervous system. It also shows antimuscarinic properties.

Alkalmazás

Clomipramine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in traditional Chinese medicine and pharmaceutical formulations by analytical and cyclodextrin-modified capillary zone electrophoresis techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analízis megjegyzés

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Egyéb megjegyzések

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Lábjegyzet

To see an example of a Certificate of Analysis for this material enter LRAC3902 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Biztonsági adatok

• Piktogramok: GHS08,GHS07,GHS09
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H302,H336,H370,H410
• Óvintézkedésre vonatkozó mondatok: P260 - P264 - P270 - P273 - P301 + P312 - P308 + P311
• Veszélyességi osztályok: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT SE 1 - STOT SE 3
• Célzott szervek: Central nervous system, Central nervous system,Cardiovascular
• Tárolási osztály kódja: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable