MABF301

Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1

clone 7B1.1, from mouse

• Szinonimák: Interleukin-7, IL-7
• UNSPSC kód: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• klón: 7B1.1, monoclonal
• application: FACS; WB
• faj reaktivitás: human
• technika/technikák: flow cytometry: suitable; western blot: suitable

Tulajdonságok

• biológiai forrás: mouse
• Minőségi szint: 100
• antitest forma: purified immunoglobulin
• antitest terméktípus: primary antibodies
• klón: 7B1.1, monoclonal
• faj reaktivitás: human
• technika/technikák: flow cytometry: suitable; western blot: suitable
• izotípus: IgG2aκ
• NCBI elérési szám: NP_000871
• UniProt elérési szám: P13232
• kiszállítva: wet ice
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... IL7(3574)

Leírás

Általános leírás

The protein named IL-7, or interleukin 7 is a hematopoietic growth factor secreted by stromal cell in the bone marrow and thymus but also produced by many other cell types including keratinocytes, epithelial cells, hepatocytes and macrophage/dendritic cells but not by classical lymphocytes. IL7 is a cytokine that has multiple functions and is critical for proper T cell maturation and lymphoid cell survival, and its expression stimulates the proliferation of B cells, T cell and NK cells. IL-7 is detected by cells via its receptor and binding results in a cascade of signals important for T cell development and for T cell survival within the periphery, as well as memory T cells. IL-7 expression is upregulated in various lymphomas and leukemias and because of its effects on T cell development IL-7 is being examined as a therapeutic agent for transplantation studies and even latent viral infection studies.

Immunogén

GST-tagged recombinant protein corresponding to human Interleukin-7/IL-7.

Alkalmazás

Flow Cytometry Analysis: 1 µg of this antibody detected recombinant Interleukin-7/IL-7 in Jurkat T and Raji B lymphocytes.

This Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1 is validated for use in western blotting & flow cytometry for the detection of Interleukin-7/IL-7.

Minőség

Evaluated by Western Blotting in Interleukin 7 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected 0.5 µg of recombinant Interleukin-7/IL-7.

Cél megnevezése

~ 17 kDa observed

Fizikai forma

Format: Purified

Egyéb megjegyzések

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Biztonsági adatok

• Tárolási osztály kódja: 12 - Non Combustible Liquids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable