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Merck
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HNDG2MAG-36K

Millipore

MILLIPLEX® Human Neurodegenerative Disease Magnetic Bead Panel 2 - Neuroscience Multiplex Assay

The analytes available for this multiplex kit are: α1-Antitrypsin, Complement C4, CRP, MIP-4, PEDF, SAP.

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

UNSPSC kód:
12161503
eCl@ss:
32161000
NACRES:
NA.84

Minőségi szint

faj reaktivitás

human

gyártó/kereskedő neve

Milliplex®

assay range

accuracy: 84%
(SAP)

accuracy: 88%
(Complement C4)

accuracy: 92%
(α-1-Antitrypsin)

accuracy: 92%
(PEDF)

accuracy: 95%
(MIP-4)

standard curve range: 0.05-200 ng/mL
(PEDF)

standard curve range: 0.10-50 ng/mL
(CRP)

standard curve range: 0.12-500 ng/mL
(SAP)

standard curve range: 0.24-1,000 ng/mL
(α-1-Antitrypsin)

standard curve range: 0.24-1,000 ng/mL
(Complement C4)

standard curve range: 4.88-20,000 ng/mL
(MIP-4)

technika/technikák

multiplexing: suitable

észlelési módszer

fluorometric (Luminex xMAP)

kiszállítva

wet ice

Általános leírás

The MILLIPLEX® Human Neurodegenerative Bead Panel 2 (HNDG2MAG-36K) is to be used for the simultaneous quantification of the following analytes in any combination: α1-Antitrypsin, Complement C4, CRP, MIP-4, PEDF, SAP.

Neurodegenerative disease is a condition characterized by the deterioration of neurons or their myelin sheath over time in the brain and/or spinal cord. These neurons are responsible for such everyday activities as processing sensory information, making decisions, and controlling movement. Because these cells are not easily regenerated, excessive cumulative damage can lead to age-related diseases such as Alzheimer′s and Parkinson′s disease, as well as other conditions such as amyotrophic lateral sclerosis (ALS) and epilepsy. These disorders are devastating and expensive, both on a personal and global level, and as population demographics continue to change, a therapeutic solution is critical. Consequently, research is underway to identify biomarkers that will help scientists not only understand the pathogenesis of neurodegenerative disease, but also identify people with these disorders before the onset of symptoms and potentially provide new therapeutic tools.

Panel Type: Neuroscience

Egyediség

Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

Alkalmazás

  • Analytes: α1-Antitrypsin, Complement C4, CRP, MIP-4, PEDF, SAP
  • Recommended Sample type: serum, plasma and CSF
  • Recommended Sample dilution: 1:2,000 diluted serum/plasma or 1:20 diluted CSF
  • Assay Run Time: Overnight
  • Research Category: Neuroscience
  • Research Subcategory: Alzheimer′s Disease Nervous System

Tulajdonságok és előnyök

Design your multiplex kit by choosing available analytes within this panel.

Kiszerelés

Everything you need in a single kit.

Tárolás és stabilitás

Recommended storage for kit components is 2 - 8°C.

Egyéb megjegyzések

Sensitivity: See kit protocol for individual sensitvities

Jogi információk

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Figyelmeztetés

Danger

Veszélyességi osztályok

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

Célzott szervek

Respiratory Tract

Tárolási osztály kódja

10 - Combustible liquids


Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

Már rendelkezik ezzel a termékkel?

Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Sean J Lee et al.
Journal of clinical & experimental ophthalmology, 6(5) (2016-01-26)
Alterations in neuron-glia signaling are implicated in glaucoma, a neurodegenerative disease characterized by retinal ganglion cell (RGC) death. Pigment epithelium derived factor (PEDF) is a secreted protein with potential neuroprotective qualities in retinal disease, including chronic ocular hypertension. Here we
Aziza Al-Rafiah et al.
BioMed research international, 2021, 3081891-3081891 (2021-10-30)
Parkinson's disease (PD) is one of the most common neurodegenerative disorders. Amphetamine addiction may cause serious of psychotic and physical damage to humans. There is some evidence that shows that amphetamine may increase the risk of PD. Thus, this study
Maria H Pham et al.
Materials (Basel, Switzerland), 13(3) (2020-02-08)
Immediately after dental implant insertion, blood will be in direct contact and interact with the implant surface and activates inflammatory responses and complement cascades within seconds. The aim of the present study was to determine the ability of fluoride-modified titanium
Abdul Hye et al.
Alzheimer's & dementia : the journal of the Alzheimer's Association, 10(6), 799-807 (2014-07-12)
The study aimed to validate previously discovered plasma biomarkers associated with AD, using a design based on imaging measures as surrogate for disease severity and assess their prognostic value in predicting conversion to dementia. Three multicenter cohorts of cognitively healthy
Felipe Mallmann et al.
Arquivos brasileiros de oftalmologia, 82(4), 275-282 (2019-04-11)
To compare the intravitreal concentrations of cellular mediators involved in neurodegeneration, inflammation, and angiogenesis in patients with proliferative diabetic retinopathy and other vitreoretinal diseases. A multiplex bead immunoassay was used to measure vitreous levels of pigment epithelium-derived factor, serum amyloid

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