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Merck
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CBL496

Sigma-Aldrich

Anti-CD34 Class II Antibody, clone QBEND/10

clone QBEND/10, Chemicon®, from mouse

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

UNSPSC kód:
12352203
eCl@ss:
32160702
NACRES:
NA.41
klón:
QBEND/10, monoclonal
application:
FACS
IHC (p)
IP
faj reaktivitás:
monkey, human
technika/technikák:
flow cytometry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
immunoprecipitation (IP): suitable
citations:
9

biológiai forrás

mouse

Minőségi szint

100
300

antitest forma

purified antibody

antitest terméktípus

primary antibodies

klón

QBEND/10, monoclonal

faj reaktivitás

monkey, human

kiszerelés

antibody small pack of 25 μg

gyártó/kereskedő neve

Chemicon®

technika/technikák

flow cytometry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
immunoprecipitation (IP): suitable

izotípus

IgG1

NCBI elérési szám

UniProt elérési szám

kiszállítva

ambient

célzott transzláció utáni módosítás

unmodified

Géninformáció

human ... CD34(947)

Egyediség

The antibody recognizes a heavily glycosylated transmembrane protein: gp 105-120 kDa. The antigen is expressed on immature human haemopoietic precursor cells, capillary endothelial cells and human myeloid cells in the following categories: subsets of CFU-GEMM and BFU-E, all CFU-GM, granulocyte precursors, monocytes, myeloid leukaemias. This antibody recognizes the class II epitope showing resistance to neuraminidase enzyme cleavage.

KNOWN SPECIES CROSS REACTIVITY: Positive with rhesus monkey peripheral blood leucocytes in flow cytometry.

FUSION PARTNER: NSO myeloma cell line

Immunogén

Human endothelial vesicles

Alkalmazás

Anti-CD34 Antibody, Class II, clone QBEND/10 is an antibody against CD34 Class II for use in FC, IP, IH, IH(P).
Identification of haemopoietic progenitor cells

Studies into the control mechanisms of early haemopoiesis

Purification of haemopoietic cells from, for example, FACS

The antibody reacts with both frozen and fixed tissue sections from vascular endothelium and stromal fibroblasts

Immunohistochemistry in parraffin sections: Pretreatment is HIER with citrate buffer, pH 6.0.

Optimal working dilutions must be determined by the end user.
Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology

Minőség

Tested

Fizikai forma

Format: Purified
The monoclonal is presented at a concentration of 100μg/1ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.

Tárolás és stabilitás

For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.

Egyéb megjegyzések

Please refer to lot specific datasheet.

Jogi információk

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Dokumentumtár megtekintése

The Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis-relapse samples of precursor B-cell acute lymphoblastic leukemia.
C E de Bock,A Ardjmand,T J Molloy,S M Bone,D Johnstone,D M Campbell,K L Shipman et al.
Leukemia null
Aisulu Usubalieva et al.
Journal of neuropathology and experimental neurology, 74(10), 960-969 (2015-09-10)
Primary meningeal gliomas are rare tumors composed of a heterogeneous group of neoplasms. We present 2 clinically aggressive cases of primary meningeal pleomorphic xanthoastrocytoma that clinically mimicked meningioma. One case presented in the posterior fossa of a 56-year-old woman; the
Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas.
Engler, JR; Robinson, AE; Smirnov, I; Hodgson, JG; Berger, MS; Gupta, N; James et al.
Testing null
Matthew D Wood et al.
Journal of neuropathology and experimental neurology, 75(10), 925-935 (2016-08-20)
Glioblastomas (GBM) are aggressive brain tumors that inevitably recur despite surgical resection, chemotherapy, and radiation. The degree to which recurrent GBM retains its initial immunophenotype is incompletely understood. We generated tissue microarrays of paired initial and posttreatment GBM (3 pairs
Takao Miki et al.
Molecular cancer research : MCR, 8(5), 665-676 (2010-04-22)
Vascular endothelial cells produce considerable amounts of matrix metalloproteinases (MMP), including MMP-2, MMP-9, and membrane type 1 (MT1)-MMP. However, little is known about the regulatory mechanisms of these protease activities exhibited during vascular development. A glycosylphosphatidylinositol-anchored glycoprotein, reversion-inducing cysteine-rich protein

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