06-984

Anti-Mn-SOD Antibody

Upstate^®, from rabbit

• Szinonimák: Mn superoxide dismutase, indophenoloxidase B, manganese superoxide dismutase, manganese-containing superoxide dismutase, mangano-superoxide dismutase, superoxide dismutase 2, mitochondrial
• UNSPSC kód: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• klón: polyclonal
• application: IHC (p); WB
• faj reaktivitás: mouse, bovine, human, rat
• technika/technikák: immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; western blot: suitable
• citations: 236

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• antitest forma: purified immunoglobulin
• antitest terméktípus: primary antibodies
• klón: polyclonal
• faj reaktivitás: mouse, bovine, human, rat
• nem léphet reakcióba: canine
• kiszerelés: antibody small pack of 25 μg
• gyártó/kereskedő neve: Upstate^®
• technika/technikák: immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; western blot: suitable
• izotípus: IgG
• NCBI elérési szám: NP_000627
• UniProt elérési szám: P04179
• kiszállítva: ambient
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... SOD2(6648)

Leírás

Általános leírás

Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn SOD/SOD1), mitochondrial manganese SOD (Mn SOD/SOD2) and extracellular Cu, Zn SOD (EC SOD/SOD3). The manganese containing 80 kDa tetrameric enzyme SOD2 is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain.

Egyediség

Recognizes MnSOD, Mr 24 kDa.

Immunogén

Recombinant human MnSOD (manganous superoxide dismutase).

Alkalmazás

Anti-Mn-SOD Antibody is an antibody against Mn-SOD for use in IH, IH(P) & WB.

Immunohistochemistry (Paraffin):
10 μg/mL of a previous lot detected MnSOD in paraffin embedded rat brain tissue sections.

Minőség

Evaluated by western blot on RIPA lysates of MCF-7, A431 or rat L6 RIPA cells.

Western Blot Analysis:
0.5-2 μg/mL of this antibody detected MnSOD in RIPA lysates of rat L6 RIPA cells. 1-4 μg/mL of a previous lot detected MnSOD in RIPA lysates of human MCF-7, A431 and rat L6 RIPA cells.

Cél megnevezése

~24 kDa

Fizikai forma

Format: Purified

Purified rabbit polyclonal in buffer containing 70% storage buffer 0.1 M Tris-glycine, pH 7.4, 0.15 M NaCl, 0.05% sodium azide and 30% glycerol.

Analízis megjegyzés

Control
L6 cell lysate, rat brain tissue extract.

Egyéb megjegyzések

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Jogi információk

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany