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Merck

719870

Sigma-Aldrich

Resomer® RG 503 H,聚(D,L-丙交酯--乙交酯)

acid terminated, lactide:glycolide 50:50, Mw 24,000-38,000

别名:

聚(D,L-丙交酯-co-乙交酯), RESOMER® RG 503 H, PLGA

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About This Item

线性分子式:
[C3H4O2]x[C2H2O2]y
MDL號碼:
分類程式碼代碼:
12162002
NACRES:
NA.23

形狀

amorphous

饋電比

lactide:glycolide 50:50

分子量

Mw 24,000-38,000

降解時間

<3 months

黏度

0.32-0.44 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

轉變溫度

Tg 44-48 °C

儲存溫度

2-8°C

SMILES 字串

OCC(O)=O.CC(O)C(O)=O

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應用

控释

特點和優勢

控释生物活性剂、缝线和可生物吸收植入器件。

外觀

具有生物相容性且可生物降解的聚合物。

法律資訊

Evonik产品
RESOMER is a registered trademark of Evonik Rohm GmbH

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Peptide or protein degradation often occurs when water flows into the dosage form. The aim of this study was to investigate the effect of water on exenatide acylation in poly(lactide-co-glycolide) (PLGA) microspheres. Exenatide-loaded PLGA microspheres were incubated at different relative
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Chronic pain after inguinal hernia repair occurs in 16% to 62% of patients. The underlying mechanism probably involves sensory nerve damage and abnormal healing that might be influenced by the materials chosen for the procedure. We hypothesize that nonabsorbable sutures
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Materials that combine facile synthesis, simple tuning of degradation rate, processability, and biocompatibility are in high demand for use in biomedical applications. We report on acetalated dextran, a biocompatible material that can be formed into microparticles with degradation rates that

商品

Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.

Synthetic aliphatic polyesters dominate resorbable biomaterials in clinical use.

商业生物材料已停滞不前超过30年的时间,因为很少有材料能够成功地从实验台过渡到临床使用。合成型脂族聚酯因其悠久的历史和获得美国食品药品监督管理局(FDA)批准的记录,一直在可吸收生物材料领域占据主导地位。

AliAliphatic polyesters, including polylactide and polyglycolide, are biodegradable polymers widely used in medical applications.

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