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Merck
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739952

Sigma-Aldrich

Resomer® RG 503，聚（D,L-丙交酯-co-乙交酯）

lactide:glycolide 50:50, ester terminated, Mw 24,000-38,000

别名:

RESOMER® RG 503

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About This Item

线性分子式:
[C3H4O2]x[C2H2O2]y
CAS号:
26780-50-7
分類程式碼代碼:
12162002
NACRES:
NA.23

形狀

amorphous

饋電比

lactide:glycolide 50:50

分子量

Mw 24,000-38,000

降解時間

<3 months

黏度

0.32-0.44 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

轉變溫度

Tg 44-48 °C

儲存溫度

2-8°C

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

InChI 密鑰

LCSKNASZPVZHEG-UHFFFAOYSA-N

相关类别

應用

控释

法律資訊

Evonik产品
RESOMER is a registered trademark of Evonik Rohm GmbH

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Kaiping Wang et al.
Journal of microencapsulation, 36(4), 356-370 (2019-06-14)
Here, we have successfully synthesised and purified multifunctional PLGA-based nanoparticles by the co-encapsulation of an anticancer drug (tetrandrine) and a magnetic material (Fe3O4). The obtained Tet-Fe3O4-PLGA NPs had a uniform spherical shape with a particle size of approximately 199 nm and
William A Lackington et al.
Journal of controlled release : official journal of the Controlled Release Society, 304, 51-64 (2019-05-06)
Neurotrophic factor delivery via biodegradable nerve guidance conduits may serve as a promising treatment for the repair of large peripheral nerve defects. However, a platform for controlled delivery is required because of their short in vivo half-life and their potential
Shu-Chun Chuang et al.
Parasites & vectors, 6, 34-34 (2013-02-13)
Current development efforts of subunit vaccines against Toxoplasma gondii, the etiological agent of toxoplasmosis, have been focused mainly on tachyzoite surface antigen 1 (SAG1). Since microparticles made from poly (lactide-co-glycolide) (PLG) polymers have been developed as safe, potent adjuvants or
Rongcai Liang et al.
International journal of pharmaceutics, 454(1), 344-353 (2013-07-23)
Peptide or protein degradation often occurs when water flows into the dosage form. The aim of this study was to investigate the effect of water on exenatide acylation in poly(lactide-co-glycolide) (PLGA) microspheres. Exenatide-loaded PLGA microspheres were incubated at different relative
Vanna Sanna et al.
International journal of nanomedicine, 7, 5501-5516 (2012-10-25)
Resveratrol, like other natural polyphenols, is an extremely photosensitive compound with low chemical stability, which limits the therapeutic application of its beneficial effects. The development of innovative formulation strategies, able to overcome physicochemical and pharmacokinetic limitations of this compound, may
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