S1198

Sumatriptan succinate

≥98% (HPLC), solid, 5-HT₁ receptor agonist

• Synonyma: 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate, GR-43175
• Empirický vzorec (Hillův zápis): C₁₄H₂₁N₃O₂S · C₄H₆O₄
• Číslo CAS: 103628-48-4
• Molekulová hmotnost: 413.49
• MDL number: MFCD00902856
• UNSPSC Code: 12352200
• PubChem Substance ID: 329824466
• NACRES: NA.77

Vlastnosti

• Název produktu: Sumatriptan succinate, ≥98% (HPLC), solid
• Quality Level: 100
• assay: ≥98% (HPLC)
• form: solid
• color: white to beige
• solubility: H₂O: >20 mg/mL
• originator: GlaxoSmithKline
• SMILES string: OC(=O)CCC(O)=O.CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1
• InChI: 1S/C14H21N3O2S.C4H6O4/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3;5-3(6)1-2-4(7)8/h4-5,8-9,15-16H,6-7,10H2,1-3H3;1-2H2,(H,5,6)(H,7,8)
• InChI key: PORMUFZNYQJOEI-UHFFFAOYSA-N
• Gene Information: human ... HTR1B(3351) , HTR1D(3352)

Popis

Biochem/physiol Actions

Sumatriptan succinate has the ability to constrict human cranial arteries. This 5-HT₁ receptor agonist can be used to treat migraine.

Sumatriptan succinate is a 5-HT1 serotonin receptor agonist.

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Bezpečnostní informace

• pictograms: GHS08
• signalword: Warning
• hcodes: H361d,H412
• pcodes: P202 - P273 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Aquatic Chronic 3 - Repr. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves