F6127

Fludrocortisone acetate

≥98%

• Synonyma: 9α-Fluoro-11β,17α,21-trihydroxy-4-pregnene-3,20-dione acetate, 9-Fluorocortisol acetate, 9-Fluorohydrocortisone acetate
• Empirický vzorec (Hillův zápis): C₂₃H₃₁FO₆
• Číslo CAS: 514-36-3
• Molekulová hmotnost: 422.49
• EC Number: 208-180-4
• MDL number: MFCD00864160
• UNSPSC Code: 12352200
• PubChem Substance ID: 24894899
• NACRES: NA.77

Vlastnosti

• biological source: synthetic
• Quality Level: 100
• sterility: non-sterile
• assay: ≥98%
• form: powder
• solubility: acetone: 50 mg/mL, clear, colorless to light yellow
• shipped in: ambient
• storage temp.: room temp
• SMILES string: CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C
• InChI: 1S/C23H31FO6/c1-13(25)30-12-19(28)22(29)9-7-16-17-5-4-14-10-15(26)6-8-20(14,2)23(17,24)18(27)11-21(16,22)3/h10,16-18,27,29H,4-9,11-12H2,1-3H3/t16-,17-,18-,20-,21-,22-,23-/m0/s1
• Inchi Key: SYWHXTATXSMDSB-GSLJADNHSA-N
• Gene Information: human ... NR3C2(4306)

Popis

General description

Fludrocortisone acetate is secreted by adrenal cortex. It increases the reabsorption of sodium and secretion of potassium and hydrogen. Fludrocortisone is used to treat cerebral salt wasting syndrome and adrenal insufficiency. Fludrocortisone improves the sensitivity of blood vessels to catecholamines and increases the blood volume.

Biochem/physiol Actions

Fludrocortisone acetate is a synthetic corticosteroid with more mineralocorticoid than glucocorticoid activity.

Bezpečnostní informace

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H361
• pcodes: P201 - P301 + P312 + P330 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable