27109

Citric acid

meets analytical specification of Ph. Eur., BP, USP, E330, anhydrous, 99.5-100.5% (based on anhydrous substance)

• Lineární vzorec: HOC(COOH)(CH₂COOH)₂
• Číslo CAS: 77-92-9
• Molekulová hmotnost: 192.12
• Beilstein/REAXYS Number: 782061
• EC Number: 201-069-1
• MDL number: MFCD00011669
• UNSPSC Code: 12352106
• eCl@ss: 39021801
• PubChem Substance ID: 329752978
• NACRES: NA.21

Vlastnosti

• Quality Level: 200
• assay: 99.5-100.5% (based on anhydrous substance)
• form: grit
• quality: anhydrous; meets analytical specification of Ph. Eur., BP, USP, E330
• expl. lim.: 8 %, 65 °F
• impurities: residual solvents, complies; ≤0.0005% heavy metals (as Pb); ≤0.5% water (Karl Fischer)
• ign. residue: ≤0.05% (as SO₄)
• pKa: (1) 3.13, (2) 4.76, (3) 6.4
• mp: 153-159 °C (lit.)
• solubility: water: 383 g/L at 25 °C
• anion traces: chloride (Cl^-): ≤50 ppm; oxalate (as oxalic acid): ≤100 ppm; sulfate (SO₄^2-): ≤100 ppm
• cation traces: As: ≤1 ppm; Ca: ≤200 ppm; Cu: ≤10 ppm; Fe: ≤10 ppm; Hg: ≤1 ppm; Pb: ≤0.5 ppm; Zn: ≤10 ppm
• suitability: complies for appearance of solution; complies for reaction against H₂SO₄
• SMILES string: OC(=O)CC(O)(CC(O)=O)C(O)=O
• InChI: 1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
• Inchi Key: KRKNYBCHXYNGOX-UHFFFAOYSA-N
• Gene Information: human ... SRC(6714)

Popis

Application

Citric acid was used as a test reagent for studying whether the novel pyridazinylpiperazine analog TPRV-1 inhibitor can reduce cough reflex induced by citric acid and capsaicin in guinea pig.

Biochem/physiol Actions

Citric acid in dietary form can augments absorption of aluminium in antacids. It also facilitates the phytoremediation of heavy metal contaminated soil and can transform cadmium into more transportable forms.

Bezpečnostní informace

• Pictograms: GHS07
• signalword: Warning
• hcodes: H319,H335
• pcodes: P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable