S9876

Sulfathiazole

• Synonyma: 2-Sulfanilamidothiazole, 4-Amino-N-(2-thiazolyl)benzenesulfonamide, N₁-(2-Thiazolyl)sulfanilamide
• Empirický vzorec (Hillův zápis): C₉H₉N₃O₂S₂
• Číslo CAS: 72-14-0
• Molekulová hmotnost: 255.32
• Beilstein/REAXYS Number: 226178
• EC Number: 200-771-5
• MDL number: MFCD00005319
• UNSPSC Code: 41116107
• PubChem Substance ID: 329824636
• NACRES: NA.24

Vlastnosti

• grade: analytical standard
• Quality Level: 100
• agency: EPA 1694
• form: powder
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• mp: 200-202 °C (lit.)
• application(s): clinical testing
• SMILES string: Nc1ccc(cc1)S(=O)(=O)Nc2nccs2
• InChI: 1S/C9H9N3O2S2/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9/h1-6H,10H2,(H,11,12)
• InChI key: JNMRHUJNCSQMMB-UHFFFAOYSA-N

Popis

General description

Sulfathiazole is a broad-spectrum antibacterial drug, belonging to the class of sulfonamides, used in veterinary and human medication for the treatment of infections. It is also involved in promoting growth of livestock and fish.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Sulfathiazole is used as an analytical reference standard for the quantification of the analyte in meat, and honey samples using different chromatography techniques.

Biochem/physiol Actions

Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.
Mode of Action: Inhibits folic acid synthesis in prokaryotes.
Anti-microbial Spectrum: Gram positive, Gram negative, Chlamydia
Mode of Resistance: Alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

Bezpečnostní informace

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335,H412
• pcodes: P261 - P264 - P271 - P273 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• ppe: dust mask type N95 (US), Eyeshields, Gloves