This product is a racemic mixture of R and S ibuprofen.
I4883
Ibuprofen
≥98% (GC), powder, COX inhibitor
Synonyma:
2-(4-Isobutylphenyl)propanoic acid, Brufen, Motrin, Rebugen, α-Methyl-4-(isobutyl)phenylacetic acid, (±)-2-(4-Isobutylphenyl)propanoic acid
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| Vám/Skladová položka | Dostupnost | Cena |
|---|---|---|
1 g | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 2 750,00 Kč |
5 g | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 4 040,00 Kč |
10 g | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 7 000,00 Kč |
O této položce
Empirický vzorec (Hillův zápis):
C13H18O2
Číslo CAS:
Molekulová hmotnost:
206.28
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
239-784-6
MDL number:
Assay:
≥98% (GC)
Form:
powder
2 750,00 Kč
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
Technický servis
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Dovolte nám, abychom vám pomohliNázev produktu
Ibuprofen, ≥98% (GC)
biological source
synthetic (organic)
Quality Segment
assay
≥98% (GC)
form
powder
mp
77-78 °C
solubility
ethanol: 50 mg/mL, clear, colorless to faintly yellow
SMILES string
CC(C)Cc1ccc(cc1)C(C)C(O)=O
InChI
1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)
InChI key
HEFNNWSXXWATRW-UHFFFAOYSA-N
Gene Information
human ... ALB(213), ALOX5(240), CYP1A2(1544), CYP2C9(1559), IL8RA(3577), PTGS1(5742), PTGS2(5743)
mouse ... Alox5(11689)
rat ... Alox5(25290), Ptgs1(24693)
General description
Ibuprofen is a commonly used nonsteroidal anti-inflammatory drug (NSAID) known for its pain-relieving, anti-inflammatory, and fever-reducing properties. It can hinder the effectiveness of various antihypertensive medications, including β-adrenergic blockers, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and diuretics. Ibuprofen exists in an unbound state in cerebrospinal fluid and is accumulated in the synovial fluid of inflamed joints in arthritis patients.
Application
Ibuprofen has been used:
- to study its vascular and pulmonary effects on neonatal lung development
- to study its effects on cell apoptosis, cell proliferation, and histology changes in human cholangiocarcinoma cell lines
- in the preparation of a terpene-based therapeutic deep eutectic system (THEDES) to investigate its physicochemical, antimicrobial, and anticancer properties
Biochem/physiol Actions
Cyclooxygenase (COX) inhibitor that has greater activity against COX-1 than against COX-2.
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Tato položka | |||
|---|---|---|---|
| form powder | form solid | form - | form crystalline |
| assay ≥98% (GC) | assay - | assay - | assay - |
| Quality Level 100 | Quality Level 200 | Quality Level 300 | Quality Level - |
| solubility ethanol: 50 mg/mL, clear, colorless to faintly yellow | solubility - | solubility - | solubility - |
| biological source synthetic (organic) | biological source - | biological source - | biological source - |
| mp 77-78 °C | mp - | mp - | mp - |
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Skladovací třída
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Is this product a racemic mixture of R and S ibuprofen?
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