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32492

Supelco

Florfenicol amine

VETRANAL®, analytical standard

Synonyma:

(αR)-α-[(1S)-1-Amino-2-fluoroethyl]-4-(methylsulfonyl)benzenemethanol, D-(−)-threo-2-Amino-3-fluoro-1-[4-(methylsulfonyl)phenyl]-1-propanol

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About This Item

Empirický vzorec (Hillův zápis):
C10H14FNO3S
Číslo CAS:
76639-93-5
Molekulová hmotnost:
247.29
MDL number:
MFCD19704818
UNSPSC Code:
41116107
PubChem Substance ID:
329754245
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@H](N)CF

InChI

1S/C10H14FNO3S/c1-16(14,15)8-4-2-7(3-5-8)10(13)9(12)6-11/h2-5,9-10,13H,6,12H2,1H3/t9-,10-/m1/s1

InChI key

XLSYLQDVLAXIKK-NXEZZACHSA-N

Související kategorie

General description

Florfenicol amine is a polar metabolite of florfenicol.

Application

Florfenicol amine may be used as an analytical reference standard for the determination of the analyte in:
  • Poultry and porcine muscle and liver by gas chromatography-negative chemical ionization mass spectrometry (GC-NCI/MS) with selected ion monitoring (SIM) detection.
  • Food samples by ultra-high performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UHPLC-ESI-MS/MS) operating in selected reaction monitoring (SRM) detection mode.
  • Chicken muscle by LC-ESI-MS/MS with multiple reaction monitoring (MRM) detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

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Osvědčení o analýze (COA)

Lot/Batch Number
BCCM1866
BCCL1842
BCCK5082
BCCJ8094
BCCH6970

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Potřebujete-li konkrétní verzi, můžete vyhledat daný certifikát podle čísla dávky nebo čísla šarže.

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Byung-Kwon Park et al.
Research in veterinary science, 84(1), 85-89 (2007-06-16)
A study on the bioavailability and pharmacokinetics of florfenicol was conducted in six healthy dogs following a single intravenous (i.v.) or oral (p.o.) dose of 20 mg kg(-1) body weight (b.w.). Florfenicol concentrations in serum were determined by a high-performance
Jianzhong Shen et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(14-15), 1523-1529 (2009-04-28)
A sensitive and reliable method using gas chromatography-negative chemical ionization mass spectrometry (GC-NCI/MS) was developed for the simultaneous determination of chloramphenicol (CAP), thiamphenicol (TAP), florfenicol (FF), and florfenicol amine (FFA) at trace levels in muscle and liver. Before extraction with
Christopher L Wrzesinski et al.
Journal of AOAC International, 86(3), 515-520 (2003-07-11)
A method for quantifying florfenicol amine (FFA) in channel catfish muscle was validated according to U.S. Food and Drug Administration guidelines. FFA is the proposed marker residue for the veterinary antibiotic florfenicol in catfish muscle for regulatory surveillance purposes. The
Jiancheng Li et al.
Journal of agricultural and food chemistry, 54(25), 9614-9619 (2006-12-07)
A study of the tissue depletion of florfenicol (FF) administered intramuscularly twice to swine at a dose rate of 20 mg per kg of body weight at 24 h intervals was carried out. Forty healthy cross swine were treated with
Arturo Anadón et al.
Journal of agricultural and food chemistry, 56(22), 11049-11056 (2008-11-04)
Chickens were used to investigate plasma disposition of florfenicol after single intravenous (i.v.) and oral dose (20 mg kg-1 body weight) and to study residue depletion of florfenicol and its major metabolite florfenicol-amine after multiple oral doses (40 mg kg-1
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