1.04351

L-Histidine

for biochemistry

• Synonyma: His, (S)-2-Amino-3-(4-imidazolyl)propionic acid, NSC 137773
• Empirický vzorec (Hillův zápis): C₆H₉N₃O₂
• Číslo CAS: 71-00-1
• Molekulová hmotnost: 155.15
• Beilstein/REAXYS Number: 84088
• MDL number: MFCD00064315
• UNSPSC Code: 12352209
• EC Index Number: 200-745-3
• NACRES: NA.21

Vlastnosti

• Quality Level: 100
• form: solid
• potency: >5110 mg/kg LD₅₀, oral (Rat)
• pH: 7.7 (20 °C, 10 g/L in H₂O)
• mp: 282 °C (dec.) (lit.)
• solubility: 38.2 g/L
• bulk density: 430 kg/m³
• storage temp.: 2-30°C
• SMILES string: N[C@@H](Cc1c[nH]cn1)C(O)=O
• InChI: 1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
• InChI key: HNDVDQJCIGZPNO-YFKPBYRVSA-N

Popis

Biochem/physiol Actions

Precursor of histamine by action of histidine decarboxylase.

Analysis Note

Assay (acidimetric, calculated on dried substance): 99.0 - 101.0 %
Identity (IR-spectrum): passes test
Appearance: white to almost white, fine-crystalline powder or colorless crystals
Appearance of solution (50 g/l; water): clear and colorless
Spec. rotation (α 20/D, 110 g/l, hydrochloric acid 120 g/l, calc. on dried substance): +11.4 to +12.4
Chloride (Cl): ≤ 200 ppm
Sulfate (SO₄): ≤ 200 ppm
Heavy metals (as Pb): ≤ 10 ppm
As (Arsenic): ≤ 5 ppm
Ca (Calcium): ≤ 10 ppm
Co (Cobalt): ≤ 5 ppm
Fe (Iron): ≤ 5 ppm
K (Potassium): ≤ 5 ppm
Mg (Magnesium): ≤ 5 ppm
Na (Sodium): ≤ 100 ppm
Zn (Zinc): ≤ 5 ppm
Ninhydrin-positive substances (LC)(any ninhydrin-positive impurity): ≤ 0.2 %
Ninhydrin-positive substances (LC) (ammonium (570 nm)): ≤ 0.02 %
Ninhydrin-positive substances (LC)(total impurities): ≤ 0.5 %
Loss on drying (105 °C; 3 h): ≤ 0.2 %

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable