53319

L-Histidine

≥99.5% (NT), BioUltra

• Synonyma: (S)-2-Amino-3-(4-imidazolyl)propionic acid, NSC 137773
• Empirický vzorec (Hillův zápis): C₆H₉N₃O₂
• Číslo CAS: 71-00-1
• Molekulová hmotnost: 155.15
• Beilstein/REAXYS Number: 84088
• EC Number: 200-745-3
• MDL number: MFCD00064315
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 57651378
• NACRES: NA.26

Vlastnosti

• Název produktu: L-Histidine, BioUltra, ≥99.5% (NT)
• product line: BioUltra
• assay: ≥99.5% (NT)
• form: powder or crystals
• optical activity: [α]20/D −39±1°, c = 2% in H₂O
• impurities: insoluble matter, passes filter test; ≤0.5% foreign amino acids
• ign. residue: ≤0.1% (as SO₄)
• loss: ≤0.5% loss on drying, 110 °C
• color: white
• pH: 7.0-8.0 (25 °C, 0.1 M in H₂O)
• mp: 282 °C (dec.) (lit.); ~285 °C (dec.)
• solubility: H₂O: 0.1 M at 20 °C, clear, colorless
• anion traces: chloride (Cl^-): ≤100 mg/kg; sulfate (SO₄^2-): ≤100 mg/kg
• cation traces: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; NH₄⁺: ≤500 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 0.1 M in H₂O
• UV absorption: λ: 260 nm A_max: 0.05; λ: 280 nm A_max: 0.05
• SMILES string: N[C@@H](Cc1c[nH]cn1)C(O)=O
• application(s): detection
• InChI: 1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
• InChI key: HNDVDQJCIGZPNO-YFKPBYRVSA-N
• Gene Information: human ... CA1(759) , CA2(760)

Popis

Application

L-Histidine has been used for characterization of ZnO nanorod in an attempt to develop a technique for the ultra-low level detection of l-histidine.

Biochem/physiol Actions

L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.

Precursor of histamine by action of histidine decarboxylase.

Other Notes

Amino acid spacing in isotachophoresis on polyacrylamide gels - a critical evaluation; Prevents circular DNA strand cleavage in a xanthine-xanthine oxidase system; Growth requirement of various microorganisms.

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)