QBD10198

NHS-dPEG^®₁₂-biotin

• Synonyma: NHS-PEG Linker, Polyethylene glycol
• Empirický vzorec (Hillův zápis): C₄₁H₇₂N₄O₁₈S
• Molekulová hmotnost: 941.09
• UNSPSC Code: 12161502
• PubChem Substance ID: 329823889
• NACRES: NA.22

Vlastnosti

• assay: >90%
• form: solid or viscous liquid
• reaction suitability: reagent type: cross-linking reagent; reaction type: Biotinylations; reactivity: amine reactive
• polymer architecture: shape: linear; functionality: monofunctional
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCC1C2NC(NC2CS1)=O)=O)ON3C(CCC3=O)=O
• InChI: 1S/C41H72N4O18S/c46-36(4-2-1-3-35-40-34(33-64-35)43-41(50)44-40)42-8-10-52-12-14-54-16-18-56-20-22-58-24-26-60-28-30-62-32-31-61-29-27-59-25-23-57-21-19-55-17-15-53-13-11-51-9-7-39(49)63-45-37(47)5-6-38(45)48/h34-35,40H,1-33H2,(H,42,46)(H2,43,44,50)
• InChI key: WOLXSUFTTIRQOU-UHFFFAOYSA-N

Popis

Features and Benefits

NHS-dPEG^®₁₂-biotin is used extensively to label molecules that contain a free amine with biotin. The single molecular weight NHS-dPEG^®₁₂-biotin has a long spacer of precise length (47.6 Å) between the biotin moiety and the labeled molecule. This dPEG^® spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the dPEG^® spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable