902934

Allyl-poly(ethylene glycol)

average M_n 5,000, PDI <1.3

• Synonyma: Allyl-PEG-OH, PEG 5k, PEG allyl, Polyethylene glycol
• Lineární vzorec: C₃H₅(C₂H₄O)_nOH
• MDL number: MFCD00020607
• UNSPSC Code: 12352112
• NACRES: NA.23

Vlastnosti

• form: powder or solid
• mol wt: PEG ~5,000 Da; average M_n 5,000
• color: off-white to pale yellow
• PDI: <1.3
• storage temp.: 2-8°C
• SMILES string: O(CCO)CC=C
• InChI: 1S/C5H10O2/c1-2-4-7-5-3-6/h2,6H,1,3-5H2
• InChI key: GCYHRYNSUGLLMA-UHFFFAOYSA-N

Popis

General description

Activated PEG derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. PEGylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of PEG improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. In addition to PEGylation, activated PEG derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity.

application

This heterobifunctional PEG has an allyl functionality on one end and an alcohol on the other. The allyl is commonly used in thiol-ene click chemistry; as well as other ligation reactions.

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable