900613

5-(4-(4-(Prop-2-yn-1-yloxy)benzoyl)phenoxy)pentanoic acid

≥95%

• Synonyma: Carboxyl benzophenone alkyne, Probe building block
• Empirický vzorec (Hillův zápis): C₂₁H₂₀O₅
• Číslo CAS: 2140866-79-9
• Molekulová hmotnost: 352.38
• MDL number: MFCD30749153
• UNSPSC Code: 12352106
• NACRES: NA.22

Vlastnosti

• Quality Level: 100
• assay: ≥95%
• form: solid
• reaction suitability: reaction type: click chemistry
• storage temp.: −20°C
• SMILES string: O(CCCCC(=O)O)c1ccc(cc1)C(=O)c2ccc(cc2)OCC#C
• InChI: 1S/C21H20O5/c1-2-14-25-18-10-6-16(7-11-18)21(24)17-8-12-19(13-9-17)26-15-4-3-5-20(22)23/h1,6-13H,3-5,14-15H2,(H,22,23)
• InChI key: PVDBYWSDYKTIBJ-UHFFFAOYSA-N

Popis

Application

5-(4-(4-(Prop-2-yn-1-yloxy)benzoyl)phenoxy)pentanoic acid is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Other Notes

Technology Spotlight: Trifuctional Probe Building Blocks

A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS

Bezpečnostní informace

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319
• pcodes: P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable