900618

3-(3-(Bromomethyl)-5-ethynylphenyl)-3-(trifluoromethyl)-3H-diazirine

95%

• Synonyma: Bromo diazirine alkyne, Probe building block
• Empirický vzorec (Hillův zápis): C₁₁H₆BrF₃N₂
• Číslo CAS: 849607-28-9
• Molekulová hmotnost: 303.08
• UNSPSC Code: 12352200
• NACRES: NA.22

Vlastnosti

• assay: 95%
• form: solid
• availability: available only in USA
• storage temp.: −20°C

Popis

Application

3-(3-(Bromomethyl)-5-ethynylphenyl)-3-(trifluoromethyl)-3H-diazirine is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Other Notes

Technology Spotlight: Trifunctional Probe Building Blocks
Design of dantrolene-derived probes for radioisotope-free photoaffinity labeling of proteins involved in the physiological Ca²⁺ release from sarcoplasmic reticulum of skeletal muscle

Bezpečnostní informace

• pictograms: GHS02
• signalword: Danger
• hcodes: H242
• pcodes: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Hazard Classifications: Self-react. C
• Storage Class: 5.2 - Organic peroxides and self-reacting hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable