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634492

4-Pyridinylboronic acid

90%

Synonyma:

4-Pyridineboronic acid, 4-Pyridylboronic acid

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Velikost baleníSkladová položkaDostupnostCena
1 g
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1 110,00 Kč
5 g
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2 880,00 Kč
2 160,00 Kč
25 g
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3 410,00 Kč

O této položce

Empirický vzorec (Hillův zápis):
C5H6BNO2
Číslo CAS:
Molekulová hmotnost:
122.92
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352103
MDL number:

1 110,00 Kč


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Quality Segment

assay

90%

form

solid

mp

>300 °C (lit.)

storage temp.

−20°C

SMILES string

OB(O)c1ccncc1

InChI

1S/C5H6BNO2/c8-6(9)5-1-3-7-4-2-5/h1-4,8-9H

InChI key

QLULGIRFKAWHOJ-UHFFFAOYSA-N

General description

4-Pyridinylboronic acid is commonly used as a reagent in cross-coupling reactions such as Suzuki-Miyaura cross-coupling.

Application

Reagent used for
  • Palladium-catalyzed Suzuki-Miyaura coupling reactions[1]
  • Ligand-free palladium-catalyzed Suzuki coupling reaction under microwave irradation

Reagent used in Preparation of
  • HIV-1 protease inhibitors[2]
  • Potential cancer threapeutics, such as PDK1 and protein kinase CK2 inhibitors[3][4]

Other Notes

Contains varying amounts of anhydride

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Tato položka
512125521418499986
assay

90%

assay

≥95.0%

assay

≥95%

assay

≥95.0%

storage temp.

−20°C

storage temp.

-

storage temp.

-

storage temp.

-

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

>350 °C (lit.)

mp

327-330 °C (lit.)

form

solid

form

solid

form

-

form

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100


Skladovací třída

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Osvědčení o analýze (COA)

Lot/Batch Number

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Sortimentní položky

Suzuki-Miyaura cross-coupling reaction is extensively used in organic chemistry, polymer science, and pharmaceutical industries.


Ligand-free, PdCl2(PPh3)2-catalyzed, microwave-assisted Suzuki coupling of 1-chloro-3-phenylisoquinoline in the synthesis of diversified 1,3-disubstituted isoquinolines
Prabakaran, K.; Nawaz Khan, F.; Jin, J. S.
Research on Chemical Intermediates, 38, 337-346 (2012)
Jorge Cruz-Huerta et al.
Chemical communications (Cambridge, England), 48(35), 4241-4243 (2012-03-23)
The combination of two heteroaromatic boronic acids with pentaerythritol gave self-complementary tectons which were suitable for the generation of 2D and 3D molecular networks.
Jin-Tao Yu et al.
Organic & biomolecular chemistry, 10(7), 1359-1364 (2011-12-20)
An efficient palladium-catalyzed Suzuki-Miyaura coupling method involving the reaction between CTV-Br(3) and a variety of aryl and heteroaryl boronic acids in the presence of indolyl phosphane ligands has been developed. This reaction procedure provided a series of C(3)-symmetric aryl-extended rigid



Globální číslo obchodní položky

Skladová položkaGTIN
634492-5G04061832722061
634492-25G04061832905365
634492-1G04061832722047

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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