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Merck

1.37117

SAFC

Dimetilsulfóxido

EMPROVE® EXPERT, Ph. Eur., ChP, USP

Fabricación farmacéutica

Sinónimos:

DMSO

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About This Item

Fórmula lineal:
(CH3)2SO
Número de CAS:
Peso molecular:
78.13
Beilstein/REAXYS Number:
506008
MDL number:
UNSPSC Code:
12352119
EC Index Number:
200-664-3

agency

ChP
Ph. Eur.
USP

Quality Level

vapor density

2.7 (vs air)

vapor pressure

0.42 mmHg ( 20 °C)

product line

EMPROVE® EXPERT

assay

≥99.9% (GC)

form

liquid

autoignition temp.

573 °F

expl. lim.

42 %, 63 °F

technique(s)

API processing | polymorph screening: suitable

refractive index

n20/D 1.479 (lit.)

kinematic viscosity

2.14 cSt

bp

189 °C (lit.)

mp

16-19 °C (lit.)

transition temp

flash point 87 °C

density

1.10 g/mL (lit.)

application(s)

liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical
semi-solid formulation

storage temp.

2-30°C

SMILES string

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Dimethyl sulfoxide is used as penetration enhancer in topical formulation, as cryopreservative in cell therapy and solvent in antibody drug conjugate production.
Due to its low microbial and endotoxin limits, Dimethyl Sulfoxide Emprove® Expert is especially suitable for high-risk applications.

Caution

Fácilmente superenfriado, vuelve a fundir lentamente a temperatura ambiente. Producto solidificado que puede volver a licuarse por calentamiento a temperatura ambiente sin detrimento del producto.

Specifications

8.0 g/m3 (20 °C)

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Artículos

Understand how considerations such as DMSO concentrations and freezing techniques are key in the successful implementation of high cell density cryopreservation (HCDC).

Find best practices for using Pellicon® Capsules in ADC processing as well as data from two studies using Pellicon® Capsules and Pellicon® cassettes in the ADC manufacturing process.

Contenido relacionado

The conjugation step in ADC production attaches a highly potent active pharmaceutical ingredient (HPAPI) to a mAb via a stable linker. Effective conjugation involves complex decisions, outlined on this page with services and products to assure success.

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