Scissione preferenziale: residui idrofobi e aromatici nelle posizioni P1 e P1′. Scinde i legami Phe-Val, Gln-His, Glu-Ala, Ala-Leu, Leu-Tyr, Tyr-Leu, Gly-Phe, Phe-Phe e Phe-Tyr nella catena β dell′insulina.
Definizione di unità
One unit will produce a change in A280 of 0.001 per minute at pH 2.0 at 37 deg C, measured as TCA-Soluble products using hemoglobin as substrate.
Risultati analitici
Il PH ottimale è compreso tra 2 e 4. Attivo in 4 M di urea e 3 M di guanidina HCl. Stabile a 60 °C. La pepsina viene inattivata irreversibilmente in presenza di pH 8,0 - 8,5.
Note legali
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
Frontiers in nutrition, 9, 833712-833712 (2022-03-01)
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