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X3629

Sigma-Aldrich

X80

≥98% (HPLC)

Sinonimo/i:

5-(5-{[1-(3-carboxyphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]methyl}-2-furyl)-2-chlorobenzoic acid

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About This Item

Formula empirica (notazione di Hill):
C23H15ClN2O6
Numero CAS:
292065-64-6
Peso molecolare:
450.83
Numero MDL:
MFCD02086439
Codice UNSPSC:
12352200
ID PubChem:
329830804
NACRES:
NA.77

Saggio

≥98% (HPLC)

Forma fisica

powder

Colore

orange

Solubilità

DMSO: >40 mg/mL

Temperatura di conservazione

2-8°C

Stringa SMILE

CC1=NN(c2cccc(c2)C(O)=O)C(=O)\C1=C/c3ccc(o3)-c4ccc(Cl)c(c4)C(O)=O

InChI

1S/C23H15ClN2O6/c1-12-17(21(27)26(25-12)15-4-2-3-14(9-15)22(28)29)11-16-6-8-20(32-16)13-5-7-19(24)18(10-13)23(30)31/h2-11H,1H3,(H,28,29)(H,30,31)/b17-11-
XZRBYOCWWJMJRZ-BOPFTXTBSA-N

Applicazioni

X80 has been used as an inhibitor of nucleotide excision repair (NER) pathway to study its effects on 8-hydroxy-2′-deoxyguanosine (8-OHdG) excision in the zygote post-fertilization.

Azioni biochim/fisiol

X80 is an inhibitor of xeroderma pigmentosum group A protein (XPA protein) required for the removal of all types of DNA lesions repaired by nucleotide excision repair Including both transcription coupled and global genomic nucleotide excision repair.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302,H413

Consigli di prudenza

P273 - P301 + P312 + P330

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Chronic 4

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Yan-Yu Cui et al.
BMC biotechnology, 21(1), 5-5 (2021-01-11)
At present, microorganism has been considered as important factors that threaten to buried pipelines with disbonded coatings. Aiming at the problem of unknown corrosion mechanism of sulfate-reducing bacteria (SRB), a series of studies have been carried out in this paper.
Qian Wu et al.
Journal of agricultural and food chemistry, 65(1), 216-223 (2016-12-16)
Anthocyanins were isolated from blueberry wine lees using Sephadex LH-20 column chromatography and semipreparative high-performance liquid chromatography (semipreparative HPLC) and then identified by HPLC-DAD-ESI-MS/MS. Our results show that malvidin-3-hexose (Mv-3-hex) and malvidin-3-(6'acetyl)-hexose (Mv-3-ace-hex) are the major components in the anthocyanin
Wendy G Cárdenas-Coronel et al.
Journal of agricultural and food chemistry, 64(1), 302-309 (2015-12-03)
Quality and compositional changes were determined in noni fruit harvested at five ripening stages, from dark-green to thaslucent-grayish. Fruit ripening was accompanied by acidity and soluble solids accumulation but pH diminution, whereas the softening profile presented three differential steps named
Xiao-Bo Dong et al.
Journal of agricultural and food chemistry, 67(4), 1261-1268 (2019-01-10)
Many organisms possess the ability to produce metal-binding proteins to absorb cadmium. Metallothioneins, an important family of cysteine-rich metal-binding proteins, have been isolated and well characterized. However, Lentinula edodes may have a different type of cadmium-binding protein that contains fewer
Fertilization stimulates 8-hydroxy-2?-deoxyguanosine repair and antioxidant activity to prevent mutagenesis in the embryo
Lord T and Aitken RJ
Developmental Biology, 406(1), 1-13 (2015)
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