U6750

Uridine 5′-triphosphate trisodium salt hydrate

Type IV, ≥93.0% (HPLC)

• Sinonimo/i: UTP Na₃
• Formula empirica (notazione di Hill): C₉H₁₂N₂Na₃O₁₅P₃ · xH₂O
• Numero CAS: 19817-92-6
• Peso molecolare: 550.09 (anhydrous basis)
• Beilstein: 3585234
• Numero CE: 243-347-5
• Numero MDL: MFCD00044310
• Codice UNSPSC: 12352200
• ID PubChem: 24900658
• NACRES: NA.77

Proprietà

• Tipo: Type IV
• Livello qualitativo: 200
• Saggio: ≥93.0% (HPLC)
• Solubilità: H₂O: soluble 25 mg of UTP in 0.5 ml of solvent, clear, colorless
• Temperatura di conservazione: −20°C
• Stringa SMILE: [Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1; MMJGIWFJVDOPJF-LLWADOMFSA-K

Descrizione

Applicazioni

UTP has been used as a P2 receptor activator to study its effects on proton efflux in MC3T3-E1 and UMR-106 cells[1]. UTP has also been studied in combination with amiloride hydrochloride in nebulizer solutions for treating cystic fibrosis[2].

Uridine 5′-triphosphate has been used in a study to show that fluoxetine (FLX), mediates its anti-depressive effect by increasing the gliotransmission of adenosine 5′-triphosphate (ATP).[3]

Azioni biochim/fisiol

Uridine-5′-Triphosphate (UTP) is a cytosolic nucleotide component of nucleic acids. It serves as a signaling molecule in the extracellular space.[4] Uridine-5′-Triphosphate (UTP) is involved in various pathophysiological responses in the nervous system. UTP also plays a major role in the regeneration process.[5]

P2Y receptor agonist.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Nota sulla preparazione

25 mg of Uridine 5′-triphosphate trisodium salt (UTP Na₃) hydrate is soluble in 0.5 ml of water and yields a clear, colorless solution.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)