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U6625

Sigma-Aldrich

Uridine 5′-triphosphate trisodium salt hydrate

from yeast, Type III, ≥96%

Sinonimo/i:

UTP Na3

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About This Item

Formula empirica (notazione di Hill):
C9H12N2Na3O15P3 · xH2O
Numero CAS:
19817-92-6
Peso molecolare:
550.09 (anhydrous basis)
Beilstein:
3585234
Numero MDL:
MFCD00044310
Codice UNSPSC:
12352200
ID PubChem:
24900436
NACRES:
NA.77

Origine biologica

yeast

Tipo

Type III

Saggio

≥96%

Solubilità

H2O: soluble 50 mg/mL, clear to slightly hazy, colorless

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O

InChI

1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1
MMJGIWFJVDOPJF-LLWADOMFSA-K

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Categorie correlate

Applicazioni

UTP has been used to study its vasodilatory effects on the skeletal muscle cells of diabetic patients. UTP has also been used as a purinergic agonist to study ion transport functions of P2Y2 receptors on rat basolateral membranes.

Azioni biochim/fisiol

P2Y receptor agonist.

Nota sulla preparazione

Uridine 5′-triphosphate trisodium salt (UTP Na3) hydrate dissolves in water at 50 mg/ml to yield a clear to slightly hazy, colorless solution.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
0000401360
0000401360
0000392559
0000392515
0000392559

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Satyanarayana R Pondugula et al.
BMC research notes, 3, 100-100 (2010-04-20)
The ionic composition of the luminal fluid in the vestibular labyrinth is maintained within tight limits by the many types of epithelial cells bounding the lumen. Regulatory mechanisms include systemic, paracrine and autocrine hormones along with their associated intracellular signal
Xiping Chen et al.
FEBS letters, 595(1), 110-122 (2020-10-25)
O-GlcNAcylation is a post-translational modification catalysed by O-GlcNAc transferase (OGT). Missense mutations in OGT have been associated with developmental disorders, OGT-linked congenital disorder of glycosylation (OGT-CDG), which are characterized by intellectual disability. OGT relies on the hexosamine biosynthetic pathway (HBP)
Alexander Puzenko et al.
The Journal of chemical physics, 137(19), 194502-194502 (2012-11-28)
In this, the third part of our series on the dielectric spectrum symmetrical broadening of water, we consider the nucleotide aqueous solutions. Where in Parts I [E. Levy et al., J. Chem. Phys. 136, 114502 (2012)] and II [E. Levy
Yinlong Yang et al.
Cell reports, 32(12), 108161-108161 (2020-09-24)
Sensing stressful conditions and adjusting the cellular metabolism to adapt to the environment are essential activities for bacteria to survive in variable situations. Here, we describe a stress-related protein, YdiU, and characterize YdiU as an enzyme that catalyzes the covalent
Lilan You et al.
Cell, 176(1-2), 239-253 (2018-12-07)
Csm, a type III-A CRISPR-Cas interference complex, is a CRISPR RNA (crRNA)-guided RNase that also possesses target RNA-dependent DNase and cyclic oligoadenylate (cOA) synthetase activities. However, the structural features allowing target RNA-binding-dependent activation of DNA cleavage and cOA generation remain
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