A6419

Adenosina 5′-trifosfato

microbial, BioReagent, suitable for cell culture, ≥99% (HPLC)

• Sinonimo/i: ATP
• Formula empirica (notazione di Hill): C₁₀H₁₄N₅Na₂O₁₃P₃ · xH₂O
• Numero CAS: 34369-07-8
• Peso molecolare: 551.14 (anhydrous basis)
• UNSPSC Code: 12352207
• eCl@ss: 32160414
• PubChem Substance ID: 24891086
• NACRES: NA.75
• MDL number: MFCD00150755
• Assay: ≥99% (HPLC)
• Form: powder

Proprietà

• biological source: microbial
• Quality Segment: 200
• product line: BioReagent
• assay: ≥99% (HPLC)
• form: powder
• technique(s): cell culture | mammalian: suitable
• solubility: H₂O: 50 mg/mL
• storage temp.: −20°C
• SMILES string: O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
• InChI key: NTBQNWBHIXNPRU-MSQVLRTGSA-L

Descrizione

General description

Adenosine 5′-triphosphate (ATP) is essential for biological processes including neurotransmission, signal transduction, muscle contraction and cardiac function. ATP is the major energy potential for living systems. They are released from cells under stress and play a key role in immune response. ATP release from injured neurons and consequent breakdown leads to generation of adenosine. ATP may serve as a therapeutic option in anaesthesia and intensive care medicine for the management of pain. Elevated ATP levels are indicative of cell damage and inflammation.

Application

Adenosine 5′-triphosphate disodium salt hydrate has been used:

• as a component of transfection mix for the transformation of CRISPR/Cas9 plasmid in parasites
• in inflammasome activation assays in bone marrow derived macrophages
• for the stimulation of macrophages
• in nucleotide synthesis

Biochem/physiol Actions

Agonista dei purinocettori P₂.

Agonista purinergico P₂; aumenta l′attività dei canali K⁺ attivati da Ca²⁺; substrato per i sistemi enzimatici ATP-dipendenti

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• wgk: WGK 2
• ppe: Eyeshields, Faceshields, Gloves, type N95 (US)
• flash_point_f: Not applicable
• flash_point_c: Not applicable