SAB5600047

Anti-BRAF (V600E) antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM8, purified immunoglobulin

• Sinonimo/i: Anti-B-RAF1, Anti-B-raf, Anti-BRAF-1, Anti-BRAF1, Anti-NS7, Anti-RAFB1
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Ricombinante: expressed in HEK 293 cells
• Livello qualitativo: 100
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: RM8, monoclonal; recombinant monoclonal
• Forma fisica: buffered aqueous glycerol solution
• Reattività contro le specie: human
• Concentrazione: ~1 mg/mL
• tecniche: ELISA: 0.5-2 μg/mL; immunoblotting: 0.5-2 μg/mL; immunocytochemistry: 0.5-5 μg/mL; immunohistochemistry: 0.5-5 μg/mL
• Isotipo: IgG
• N° accesso NCBI: 673
• N° accesso UniProt: P15056
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... BRAF(673)

Descrizione

Descrizione generale

BRAF (B-Raf proto-oncogene) is a serine-threonine kinase, that codes for B-Raf protein. It is located on human chromosome 7q34.

Specificità

This antibody reacts to the BRAF V600E mutant. No cross reactivity with wild type BRAF.

Immunogeno

Peptide corresponding to BRAF V600E mutant

Azioni biochim/fisiol

BRAF (B-Raf proto-oncogene) participates in signaling direct cell growth. It induces tumor growth by initiating the mitogen-activated protein kinase (MAPK) pathway in various tumors like cutaneous melanoma and carcinomas of the thyroid and colon.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable