This product is supplied as a neat or pure liquid with a density of 0.925 g/mL and a molecular weight of 145.25 g/mol. The minimum purity is 99%, thus the molarity will vary slightly from lot to lot. The molarity can range from 6.3 M ( 99%) to 6.4 M (100%). The lot-specific purity is reported on the Certificate of Analysis.
S2626
Spermidine
Spermidine
1 of 1 reviewers received a sample product or took part in a promotion
≥99% (GC)
Sinonimo/i:
1,8-Diamino-4-azaoctane, N-(3-Aminopropyl)-1,4-diaminobutane
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1 G
CHF 63.80
5 G
CHF 251.00
25 G
CHF 812.00
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Cambia visualizzazione
1 G
CHF 63.80
5 G
CHF 251.00
25 G
CHF 812.00
About This Item
Formula condensata:
NH2(CH2)3NH(CH2)4NH2
Numero CAS:
Peso molecolare:
145.25
Beilstein:
1698591
Numero CE:
Numero MDL:
Codice UNSPSC:
12352200
ID PubChem:
NACRES:
NA.32
Prodotti consigliati
Origine biologica
synthetic
Saggio
≥99% (GC)
Stato
solid or liquid (clear)
Impurezze
DNase, none detected
RNase, none detected
protease, none detected
Indice di rifrazione
n20/D 1.479 (lit.)
Punto di fusione
22-25 °C
Solubilità
water: 50 mg/mL, clear to very slightly hazy, colorless to very faintly yellow
Densità
0.925 g/mL at 25 °C (lit.)
Temperatura di conservazione
room temp
Stringa SMILE
NCCCCNCCCN
InChI
1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2
ATHGHQPFGPMSJY-UHFFFAOYSA-N
Informazioni sul gene
rat ... Ppm1a(24666)
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Descrizione generale
Spermidine, a natural biomolecule, is known for its wide-ranging health benefits, including anti-inflammatory effects, antioxidant properties, and improvements in respiratory function. It carries a positive charge at physiological pH, allowing it to interact with oppositely charged DNA and RNA. Dietary intake of spermidine is associated with a reduced risk of neurodegeneration, metabolic diseases, heart ailments, and cancer. Spermidine-induced autophagy has been shown to slow the rate of cognitive decline by clearing amyloid-beta plaques in the brain. Spermidine supplementation improves mitochondrial metabolism and translational activity. Moreover, spermidine exhibits cell-autonomous effects on cancer cells and influences their communication with immune effectors, leading to the acceleration of tumor-associated antigen identification and cancer cell death. Spermidine-mediated autophagy inhibits the activation of apoptosis in cancer cells and is linked to tissue development and cell differentiation. This natural compound is additionally recognized for its neuroprotective, and anti-aging properties and is naturally found in semen, as well as in various plant sources.[1]
The enzyme nitric oxide synthase (nNOS) is involved in the production of nitric oxide.[2]
Applicazioni
Azioni biochim/fisiol
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T4 polynucleotide kinase activity.
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.
Avvertenza
Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.
Altre note
Store under inert gas. Air sensitive; strongly hygroscopic.
Prodotti correlati
N° Catalogo
Descrizione
Determinazione del prezzo
Avvertenze
Danger
Indicazioni di pericolo
Classi di pericolo
Eye Dam. 1 - Skin Corr. 1B
Codice della classe di stoccaggio
8A - Combustible corrosive hazardous materials
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
233.6 °F - closed cup
Punto d’infiammabilità (°C)
112 °C - closed cup
Dispositivi di protezione individuale
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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We have purchased S2626 spermidine 5 g. It does not say anywhere what molar concentration or if it is actually dissolved in water. Could you please inform me about that. I received 5 g i aprox 4 ml, and as I can read, the solubility is 50 mg /ml. ???
1 answer-
Helpful?
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Is the Molarity for all Spermidin batches the same ? Does the 6,4 M count also for xx-1G and xx-25G?
1 answer-
The molarity of this compound is the same for all pack sizes, but may vary slightly from lot to lot. The reported 6.4 M is assuming a 100% purity. The minimum purity specification is 99%.
Helpful?
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What is the molarity of Spermidine S2626-5G solution and what is the longterm storage condition?
1 answer-
This product is a neat or pure liquid. Based on a density of 0.925 g/mL and a molecular weight of 145.25, this material has an effective molarity of 6.4 M. It is recommended to store this solution as single-use aliquots at -20 ºC for no more than one month.
Helpful?
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Helpful?
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Is this a spermidine solution or a neat liquid, and what is the concentration?
1 answer-
Based on a density of 0.925 g/mL and a molecular weight of 145.25, this neat liquid has an effective molarity of 6.4 M.
Helpful?
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