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P1742

Sigma-Aldrich

Prealbumin from human plasma

lyophilized powder

Sinonimo/i:

Thyroxine binding prealbumin, Transthyretin

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About This Item

Numero CAS:
Numero MDL:
Codice UNSPSC:
12352202
NACRES:
NA.25

Origine biologica

human plasma

Livello qualitativo

Saggio

≥95% (SDS-PAGE)

Forma fisica

lyophilized powder

tecniche

immunoelectrophoresis: suitable
immunoprecipitation (IP): suitable

Solubilità

H2O: soluble 1 mg/mL

ε (coefficiente d’estinzione)

13.5 at 280 nm at 1%

N° accesso UniProt

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... TTR(7276)

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Descrizione generale

Human prealbumin is a product of chromosome 18. It is a serum protein, synthesized primarily in the liver. It is a tetrameric protein with a molecular weight of 55 kDa. Human prealbumin is composed of four identical non-covalently bound monomers of 127 amino acid residues arranged with tetrahedral symmetry.

Applicazioni

Human prealbumin was used to study reduced transthyretin expression in sera of lung cancer.
Prealbumin from human plasma has been used as a positive control in immunoprecipitation as a reference standard in quantitative rocket immunoelectrophoresis for quantification of cerebrospinal fluid.

Azioni biochim/fisiol

Human prealbumin has been observed in carcinoid tumors.
Prealbumin levels are indictors of malnutrition and may be modulated during inflammation. It is regarded as potential marker of protein energy malnutrition (PEM) during chronic kidney failure supported dialysis. Low levels of prealbumin poses high risk to heart failure (HF).

Confezionamento

Package size based on protein content

Stato fisico

Lyophilized powder containing sodium phosphate and NaCl

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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