Passa al contenuto
Merck
Tutte le immagini(2)

Documenti fondamentali

O1383

Sigma-Aldrich

Acido oleico

BioReagent, suitable for cell culture

Sinonimo/i:

Acido cis-9-ottadecenoico, Acido elainico

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Formula condensata:
CH3(CH2)7CH=CH(CH2)7COOH
Numero CAS:
Peso molecolare:
282.46
Beilstein:
1726542
Numero CE:
Numero MDL:
Codice UNSPSC:
12352211
ID PubChem:
NACRES:
NA.75
Prezzi e disponibilità al momento non sono disponibili

Origine biologica

palm oil

Livello qualitativo

Tensione di vapore

1 mmHg ( 176 °C)

Nome Commerciale

BioReagent

Saggio

≥99% (GC)

Stato

viscous liquid

tecniche

cell culture | mammalian: suitable

Indice di rifrazione

n20/D 1.459 (lit.)

P. ebollizione

194-195 °C/1.2 mmHg (lit.)

Punto di fusione

13-14 °C (lit.)

Solubilità

ethanol: soluble

Densità

0.89 g/mL at 25 °C (lit.)
0.89 g/mL at 25 °C (lit.)

Temperatura di conservazione

−20°C

Stringa SMILE

CCCCCCCC\C=C/CCCCCCCC(O)=O

InChI

1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
ZQPPMHVWECSIRJ-KTKRTIGZSA-N

Informazioni sul gene

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

Oleic acid is a mono-unsaturated omega-9 fatty acid created by dehydrogenation of stearic acid. It is then further dehydrogenated and elongated to create members of the n-9 family of fatty acids. Oleic acid is not an essential fatty acid (EFA); however, providing it to cells in culture reduces energy demand.
Oleic acid mediates complete oxidation of fatty acid in sirtuin1- proliferator-activated receptor γ coactivator−1α (SIRT1-PGC-1α) signalling pathway. Oleic acid shows anti-inflammatory properties related to atherosclerosis and insulin resistant state.[1] Oleic acid inhibits permeability in gap junctions and promotes glucose uptake in astrocytes. Oleic acid aids in neural cell proliferation by increasing glucose uptake and by protein kinase C (PKC) activation. Oleic acid is essential for axonal growth and neuronal clustering.[2]

Applicazioni

Oleic acid has been used:
  • in fatty acid oxidation rate experiments in myotubes and in Sirt1 enzyme assay[1]
  • to determine quantitatively its effect on lipid droplets by optical diffraction tomography[3]
  • as a fatty acid source in the medium for primary hepatocyte culture[4]

Confezionamento

Sealed ampule.

Avvertenza

Unsaturated fatty acids are subject to oxidation and peroxidation. Consider complexed fatty acid supplements.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Dispositivi di protezione individuale

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 6

1 of 6

Three-dimensional label-free imaging and quantification of lipid droplets in live hepatocytes
Kim K, et al.
Scientific Reports, 6(10), 36815-36815 (2016)
Beneficial effect of fish oil on human brain (2009)
Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1alpha complex
Lim JH, et al.
The Journal of Biological Chemistry, 288(10), 7117-7126 (2013)
The role of proliferator-activated receptor gamma coactivator-1alpha in the fatty-acid-dependent transcriptional control of interleukin-10 in hepatic cells of rodents
Morari J, et al.
Metabolism, Clinical and Experimental, 59(2), 215-223 (2010)
Joyce Wang et al.
BMC genomics, 15, 415-415 (2014-06-03)
Mycobacterium avium subsp. paratuberculosis (MAP) is an obligate intracellular pathogen that infects many ruminant species. The acquisition of foreign genes via horizontal gene transfer has been postulated to contribute to its pathogenesis, as these genetic elements are absent from its

Articoli

Lipid Induced Insulin Resistance

Questions

1–3 of 3 Questions  
  1. What is the concentration of this oleic acid and what solvent do I need to make dilution

    1 answer
    1. This product is a neat or pure liquid and has not been diluted. This material has a density of 0.890 g/mL and a molecular weight of 282.46 g/mol. The minimum purity is 99%, thus the molarity will vary slightly from lot to lot. The molarity can range from 3.12 M (99%) to 3.15 M (100%).

      Helpful?

  2. What is the concentration of this product-O1383-25G?

    1 answer
    1. The concentration of this product can be determined using the lot-specific purity reported in the Certificate of Analysis, as well as the density and compound molecular weight. This product has a density of 0.89 g/mL and a molecular weight of 282.46 g/mol. The minimum purity is 99%, thus the molarity will vary slightly from lot to lot. The molarity can range from 3.12 M (99%) to 3.15 M (100%).

      Helpful?

  3. Has product O1383-25g been received in a glass container or ampule?

    1 answer
    1. Based on the packaging information, product O1383-25g has been received in a glass ampule.

      Helpful?

Reviews

No rating value

Active Filters

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.