L9150

N-lauroil-sarcosina

detergent for use in cell lysis

• Sinonimo/i: N-dodecanoil-N-metil-glicina, Sarcosil NL
• Formula condensata: CH₃(CH₂)₁₀CON(CH₃)CH₂COONa
• Numero CAS: 137-16-6
• Peso molecolare: 293.38
• Beilstein: 5322974
• Numero CE: 205-281-5
• Numero MDL: MFCD00042728
• Codice UNSPSC: 12161902
• ID PubChem: 57654340
• NACRES: NA.52

Proprietà

• Grado: for molecular biology
• Descrizione: anionic
• Nome Commerciale: BioReagent
• Saggio: ≥94%
• Forma fisica: powder
• PM: micellar avg mol wt 600
• Numero d'aggregazione: 2
• tecniche: protein purification: suitable; protein quantification: suitable
• CMC: 14.6 mM (20-25°C)
• Solubilità: H₂O: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
• Attività estranea: DNase, RNase, none detected
• Temperatura di conservazione: room temp
• Stringa SMILE: [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O
• InChI: 1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1; KSAVQLQVUXSOCR-UHFFFAOYSA-M

Descrizione

Descrizione generale

Sodium lauroyl sarcosinate, the sodium salt of an acyl derivative of sarcosine—a natural amino acid occurring in muscles and body tissues—stands out as a valuable component in molecular biology, biochemical, and cell biology research. Derived from a natural fatty acid and the amino acid derivative sarcosine, N-Lauroylsarcosine is a biodegradable anionic surfactant usually synthesized through acylation and neutralization reactions involving lauric acid and sodium sarcosine.

This amino acid-type anionic surfactant, also recognized as a fatty acid amide and detergent, exhibits protein denaturant potency and has been integrated into lysing solutions, such as the cornet assay. Its application extends to lysing protoplasts for chromosomal DNA isolation from Streptococcus mutans. Notably, Lauroylsarcosine Sodium Salt, characterized by its ionic detergent properties, is commonly employed for purifying membrane proteins. Additionally, Sodium Lauroyl Sarcosine also plays a crucial role in concentrated salt solutions, facilitating cell lysis in RNA purification protocols and membrane solubilization. Whether it′s breaking down cell structures or facilitating membrane protein purification, this mild surfactant proves valuable in various applications within the realms of biology and biochemistry.

Applicazioni

Suitable for

• solubilization and separation of membrane proteins
• lysis of cells during the isolation of RNA
• inhibition of hexokinase

Caratteristiche e vantaggi

• Suitable for Molecular Biology, Biochemical and Cell Biology research
• Can be used for Protein Purification and Quantification
• High purity product for research applications

Altre note

Tensioattivo anionico.

For additional information on our range of Biochemicals, please complete this form.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS05
• Avvertenze: Danger
• Indicazioni di pericolo: H315,H318,H330
• Consigli di prudenza: P260 - P264 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2
• Codice della classe di stoccaggio: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 512.6 °F - closed cup
• Punto d’infiammabilità (°C): 267 °C - closed cup
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)