61743

N-lauroil-sarcosina

BioUltra, for molecular biology, ≥99.0% (HPLC)

• Sinonimo/i: N-dodecanoil-N-metil-glicina, Sarcosil NL
• Formula condensata: CH₃(CH₂)₁₀CON(CH₃)CH₂COONa
• Numero CAS: 137-16-6
• Peso molecolare: 293.38
• Beilstein: 5322974
• Numero CE: 205-281-5
• Numero MDL: MFCD00042728
• Codice UNSPSC: 12161900
• ID PubChem: 57651862
• NACRES: NA.25

Proprietà

• Grado: Molecular Biology; for molecular biology
• Livello qualitativo: 200
• Descrizione: anionic
• Nome Commerciale: BioUltra
• Saggio: ≥99.0% (HPLC)
• Stato: powder
• PM: micellar avg mol wt 600; average mol wt 600
• Numero d'aggregazione: 2
• Impurezze: DNases, none detected; RNases, none detected; insoluble matter, passes filter test; phosphatases, none detected; proteases, none detected
• Perdita: ≤1% loss on drying, 110 °C
• pH: 7.0-9.0 (25 °C, 1 M in H₂O)
• CMC: 14.6 mM (20-25°C)
• Solubilità: H₂O: 1 M at 20 °C, clear, colorless
• Anioni in tracce: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• Cationi in tracce: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 1 M in H₂O
• Stringa SMILE: [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O
• Assorbanza UV: λ: 260 nm A_max: 0.2; λ: 280 nm A_max: 0.06
• applicazioni: sample preservation
• InChI: 1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1; KSAVQLQVUXSOCR-UHFFFAOYSA-M

Descrizione

Descrizione generale

The N-lauroylsarcosine sodium salt is applicable for processes that require tight control of elemental content. This product aids in the solubilization and separation of membrane proteins, glycoproteins, and the isolation of RNA and plasmids. N-lauroylsarcosine sodium salt serves as an antifoaming supplement or as a component of a lysing buffer of bacteria or other cells. It indicates the paramagnetic anisotropy sign change in the micelle mesophase. N-lauroylsarcosine sodium salt inhibits hexokinase and the bacterial flora of human saliva/gut at 0.25%. It also exhibits fungistatic activity in aqueous dispersion (1%). N-lauroylsarcosine (LS) is an anionic surfactant with protein denaturant potency that is structurally similar to sodium lauryl sulfate (SLS). It can inactivate herpes simplex virus (HSV) infectivity in vitro. It is used as a microbicide in topical vaginal formulations to block the transmission of HSV, human immunodeficiency virus type 1 (HIV-1), and possibly other pathogens causing sexually transmitted diseases (STDs).[1]

Applicazioni

N-Lauroylsarcosine sodium salt has been used as a component:

• of nuclease stop mix, embryo extract buffer to dissociate nonspecifically bound proteins from chromatin
• of proteinase K solution for the heat denaturation of genomic DNA
• of 10% (w/v) sarcosyl/0.5 M ethylenediaminetetraacetic acid (EDTA) solution to prepare EDTA-sarcosyl-proteinase (ESP) buffer
• in the hybridization buffer for in situ hybridization histochemistry[2]
• in the embryo extract buffer to dissociate nonspecifically bound proteins from chromatin[3]
• in proteinase K solution to inactivate the enzymes[4]

Altre note

Tensioattivo anionico.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS05
• Avvertenze: Danger
• Indicazioni di pericolo: H315,H318,H330
• Consigli di prudenza: P260 - P264 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2
• Codice della classe di stoccaggio: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 512.6 °F - closed cup
• Punto d’infiammabilità (°C): 267 °C - closed cup
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)