850355P

16:0 PC (DPPC)

Avanti Research^™ - A Croda Brand

• Sinonimo/i: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine; DPPC; PC(16:0/16:0)
• Formula empirica (notazione di Hill): C₄₀H₈₀NO₈P
• Numero CAS: 63-89-8
• Peso molecolare: 734.04
• Numero MDL: MFCD00036903
• Codice UNSPSC: 51191904
• NACRES: NA.25

Proprietà

• Descrizione: 1,2-dipalmitoyl-sn-glycero-3-phosphocholine
• Saggio: >99% (TLC)
• Stato: powder
• Confezionamento: pkg of 1 × 1 g (850355P-1g); pkg of 1 × 200 mg (850355P-200mg); pkg of 1 × 25 mg (850355P-25mg); pkg of 1 × 500 mg (850355P-500mg)
• Produttore/marchio commerciale: Avanti Research^™ - A Croda Brand
• Tipo di lipide: phospholipids; cardiolipins
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• Stringa SMILE: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
• InChI: 1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3; KILNVBDSWZSGLL-UHFFFAOYSA-N

Descrizione

Descrizione generale

1,2-dihexadecanoyl-sn-glycero-3-phosphocholine (DPPC) is synthesized from unsaturated phosphatidylcholine (PC) by direct de novo synthesis via α1,2-dipalmitoyl diacylglycerol intermediate. The enzyme cholinephosphotransferase catalyzes the conversion of 1,2-dipalmitoyl diacylglycerol to DPPC. Synthesis of DPPC also occurs via remodeling pathway involving deacylation of unsaturated PC.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Applicazioni

16:0 PC (DPPC) has been used in the generation of thymoquinone (TQ) liposomes, gold nanorods and calcium chloride encapsulated liposomes and bilayers for biophysical studies.

Azioni biochim/fisiol

1,2-dihexadecanoyl-sn-glycero-3-phosphocholine (DPPC) is a surfactant and reduces surface tension. It is used in combination with 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) for lipid bilayer generation. DPPC alone and in combination with other phospholipid is effective in drug encapsulation and delivery.

Confezionamento

20 mL Clear Glass Screw Cap Vial (850355P-1g)

20 mL Clear Glass Screw Cap Vial (850355P-500mg)

5 mL Amber Glass Screw Cap Vial (850355P-200mg)

5 mL Amber Glass Screw Cap Vial (850355P-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable