900600

3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid

≥95%

• Sinonimo/i: Carboxyl sulfonyl fluoride alkyne, Probe building block
• Formula empirica (notazione di Hill): C₁₂H₁₃FO₄SSi
• Numero CAS: 2088829-06-3
• Peso molecolare: 300.38
• Numero MDL: MFCD30737995
• Codice UNSPSC: 12352106
• NACRES: NA.22

Proprietà

• Saggio: ≥95%
• Forma fisica: solid
• Impiego in reazioni chimiche: reagent type: cross-linking reagent
• Disponibilità: available only in USA
• Temperatura di conservazione: −20°C
• Stringa SMILE: O=S(C1=CC(C#C[Si](C)(C)C)=CC(C(O)=O)=C1)(F)=O

Descrizione

Applicazioni

3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Altre note

Technology Spotlight: Trifuctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H242,H315,H319
• Consigli di prudenza: P210 - P235 - P302 + P352 - P305 + P351 + P338 - P370 + P378 - P403
• Classi di pericolo: Eye Irrit. 2 - Self-react. C - Skin Irrit. 2
• Codice della classe di stoccaggio: 5.2 - Organic peroxides and self-reacting hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable